Retroviral Membrane Fusions: Regulation by Proteolytic Processing and Cellular Factors

Kubo, Yasuo

doi:10.1007/978-90-481-9772-9_3

Search citation statements

Order By: Relevance

Paper Sections

Select...

Cell Fusion and Stem Cells1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 125 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Viruses are dependent on host cells, which they can infiltrate and abuse for the replication of viral genetic information. Thereby, some of this viral genetic information became integrated into the human genome and interestingly normal human cells expressing retroviral envelope proteins have shown an increased fusogenecity [121][122][123]. A second disease in which cell fusion events might play a role is cancer (Table 3).…”

Section: Cell Fusion and Stem Cellsmentioning

confidence: 99%

The Role of MSCs and Cell Fusion in Tissue Regeneration

Dörnen

Dittmar

2021

IJMS

View full text Add to dashboard Cite

Regenerative medicine is concerned with the investigation of therapeutic agents that can be used to promote the process of regeneration after injury or in different diseases. Mesenchymal stem/stromal cells (MSCs) and their secretome – including extracellular vesicles (EVs) are of great interest, due to their role in tissue regeneration, immunomodulatory capacity and low immunogenicity. So far, clinical studies are not very conclusive as they show conflicting efficacies regarding the use of MSCs. An additional process possibly involved in regeneration might be cell fusion. This process occurs in both a physiological and a pathophysiological context and can be affected by immune response due to inflammation. In this review the role of MSCs and cell fusion in tissue regeneration is discussed.

show abstract

Section: Cell Fusion and Stem Cellsmentioning

confidence: 99%