Preetha Anand, Hareesh B. Nair, Bokyung Sung, Ajaikumar B. Kunnumakkara, Vivek R. Yadav, Rajeshwar R. Tekmal, Bharat B. Aggarwal
Curcumin, a yellow pigment present in the spice turmeric (Curcuma longa), has been linked with antioxidant, anti-inflammatory, anti-proliferative, anticancer, antidiabetic, antirheumatic, and antiviral effects, but its optimum potential is limited by its lack of solubility in aqueous solvents and poor oral bioavailability. We employed a polymer-based nanoparticle approach to improve bioavailability. Curcumin was encapsulated with 97.5% efficiency in biodegradable nanoparticulate formulation based on poly (lac…
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