Retinoschisis in Pars Planitis

Case Report: A case of unexplained retinoschisis

“…Because VMT, optic pits, and glaucoma were absent, we questioned whether a relationship was present between the occurrence of retinoschisis and intraocular inflammation. Some investigators have presumed that retinoschisis is a result of neovascularization, inflammatory exudates, and accumulation of fluid within the retina ( 10 ) or a result of vascular abnormalities (specifically intraretinal leakage from telangiectatic retinal vessels) rather than a result of tractional forces ( 11 ). Inflammation may result in complex cellular reactions involving a variety of cytokine-and angiogenesis-mediated retinal vascular changes, including vascular dilation and neovascularization.…”

Case Report: A case of unexplained retinoschisis

“…Because VMT, optic pits, and glaucoma were absent, we questioned whether a relationship was present between the occurrence of retinoschisis and intraocular inflammation. Some investigators have presumed that retinoschisis is a result of neovascularization, inflammatory exudates, and accumulation of fluid within the retina ( 10 ) or a result of vascular abnormalities (specifically intraretinal leakage from telangiectatic retinal vessels) rather than a result of tractional forces ( 11 ). Inflammation may result in complex cellular reactions involving a variety of cytokine-and angiogenesis-mediated retinal vascular changes, including vascular dilation and neovascularization.…”

Total exudative retinal detachment in a child with pars planitis- a challenging case with optimistic results

“…Brockhurst [ 5 ] described that retinoschisis in chronic peripheral uveitis developed after several years of active disease, with massive exudation overlying the inferior portions of the ora serrata. Treatment of this form of retinoschisis was rarely necessary, with only one case needing wide scleral buckling with subsequent drainage of fluid due to progression [ 5 ]. Similarly, Pollack et al [ 4 ] reported that the schisis/ERD remained stable in 9 of 13 eyes.…”

“…It is hypothesized that traction occurs due to contraction of snowbanking caused both tangential and radial traction on the pars plana and peripheral retina leading to peripheral retinal elevation. The elevation subsequently relieves further traction, explaining the lack of progression in the majority of cases [ 5 , 6 ].…”

Intermediate Uveitis

“…Nonprogressive tractional elevations can be observed [125]. Progression of retinoschisis can be observed in active or inactive uveitis, but may require surgery to repair retinal detachment [126].…”

Case Report: A case of unexplained retinoschisis

“…Because VMT, optic pits, and glaucoma were absent, we questioned whether a relationship was present between the occurrence of retinoschisis and intraocular inflammation. Some investigators have presumed that retinoschisis is a result of neovascularization, inflammatory exudates, and accumulation of fluid within the retina ( 10 ) or a result of vascular abnormalities (specifically intraretinal leakage from telangiectatic retinal vessels) rather than a result of tractional forces ( 11 ). Inflammation may result in complex cellular reactions involving a variety of cytokine-and angiogenesis-mediated retinal vascular changes, including vascular dilation and neovascularization.…”

Total exudative retinal detachment in a child with pars planitis- a challenging case with optimistic results

“…Brockhurst [ 5 ] described that retinoschisis in chronic peripheral uveitis developed after several years of active disease, with massive exudation overlying the inferior portions of the ora serrata. Treatment of this form of retinoschisis was rarely necessary, with only one case needing wide scleral buckling with subsequent drainage of fluid due to progression [ 5 ]. Similarly, Pollack et al [ 4 ] reported that the schisis/ERD remained stable in 9 of 13 eyes.…”

“…It is hypothesized that traction occurs due to contraction of snowbanking caused both tangential and radial traction on the pars plana and peripheral retina leading to peripheral retinal elevation. The elevation subsequently relieves further traction, explaining the lack of progression in the majority of cases [ 5 , 6 ].…”

Intermediate Uveitis

“…Nonprogressive tractional elevations can be observed [125]. Progression of retinoschisis can be observed in active or inactive uveitis, but may require surgery to repair retinal detachment [126].…”

Case Report: A case of unexplained retinoschisis

“…Because VMT, optic pits, and glaucoma were absent, we questioned whether a relationship was present between the occurrence of retinoschisis and intraocular inflammation. Some investigators have presumed that retinoschisis is a result of neovascularization, inflammatory exudates, and accumulation of fluid within the retina ( 10 ) or a result of vascular abnormalities (specifically intraretinal leakage from telangiectatic retinal vessels) rather than a result of tractional forces ( 11 ). Inflammation may result in complex cellular reactions involving a variety of cytokine-and angiogenesis-mediated retinal vascular changes, including vascular dilation and neovascularization.…”

Total exudative retinal detachment in a child with pars planitis- a challenging case with optimistic results

“…Brockhurst [ 5 ] described that retinoschisis in chronic peripheral uveitis developed after several years of active disease, with massive exudation overlying the inferior portions of the ora serrata. Treatment of this form of retinoschisis was rarely necessary, with only one case needing wide scleral buckling with subsequent drainage of fluid due to progression [ 5 ]. Similarly, Pollack et al [ 4 ] reported that the schisis/ERD remained stable in 9 of 13 eyes.…”

“…It is hypothesized that traction occurs due to contraction of snowbanking caused both tangential and radial traction on the pars plana and peripheral retina leading to peripheral retinal elevation. The elevation subsequently relieves further traction, explaining the lack of progression in the majority of cases [ 5 , 6 ].…”

Intermediate Uveitis

“…Nonprogressive tractional elevations can be observed [125]. Progression of retinoschisis can be observed in active or inactive uveitis, but may require surgery to repair retinal detachment [126].…”