Retinopathy of prematurity in babies weighing &lt;1800 g; with special reference to babies weighing between 1501 and 1800 g: An experience from a tertiary care hospital in Delhi

Kapoor, Rohit; Talwar, Richa; Sachdeva, Sandeep; Paul, Premila; Yadav, Rakesh; Sachdeva, Sarthak

doi:10.4103/2230-8598.144066

Cited by 7 publications

(10 citation statements)

References 10 publications

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“…A study done by Charan R et al had screened all babies <1700 gm for ROP. 14 16 The present study was an attempt to find incidence for ROP by newer guidelines from Government of India, published under the Rashtriya Bal Swasthya Karyakram (RBSK) which include screening of all newborns <2 kg and in present study it had shown the significant incidence of ROP in >1.5 kg newborns. 7 In present study incidence of ROP was 24.1% which was similar like in Maheshwari R et al, (20%), Chaudhari S et al, (22.3%) and Goyal A et al, (25.4%).…”

Section: Discussionmentioning

confidence: 74%

“…Kumar P et al and Kapoor R et al both found Respiratory Distress Syndrome (RDS) as a significant independent risk factor for ROP in multivariate analysis. 5,16 While Maini B et al and Le c et al, on univariate analysis found that by giving complete dose of antenatal steroid, risk of developing ROP were decreased. 15,22 Hence by giving complete dose of antenatal steroid we can prevent occurrence of ROP directly and indirectly by decreasing incidence of Respiratory Distress Syndrome (RDS).…”

Section: Discussionmentioning

confidence: 98%

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Retinopathy of prematurity in India: incidence, risk factors, outcome and the applicability of current screening criteria

Patel

Shendurnikar

2019

Int J Contemp Pediatr

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Background: To study the incidence, risk factors and outcome of retinopathy of prematurity (ROP) in at-risk newborns at tertiary care hospital in Vadodara.Methods: Preterm infants with birth weight ≤2000 gm and gestation ≤34 weeks were screened for ROP at 4 weeks of birth for first screening or if <28 week or <1200 grams then at 3 weeks after delivery. Infants with birth weight >2000 gm and gestation >34 weeks were screened only if they had additional risk factors. Those found to have high risk ROP were treated.Results: The incidence of ROP in 286 infants who were screened was 24.1%, 12 ROP positive cases were having birth weight >2000 gm. On multivariate analysis risk factors predisposing to ROP (P<0.05) were birth asphyxia, Sepsis, multiple blood transfusion, respiratory distress syndrome, multiple birth, antenatal steroid use and Phototherapy. Out of 69 infants who developed ROP, 6(8.7%) needed invasive management.Conclusions: Risk factors predisposing to ROP were gestational age and birth weight alone and along with the various risk factors like birth asphyxia, sepsis, multiple blood transfusion, respiratory distress syndrome, multiple birth, antenatal steroid use and phototherapy. The occurrence of ROP is trending towards a rise including newborns with higher birth weight and gestational age in developing countries; hence necessitating to use different guideline for Screening of Newborns in these developing countries.

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Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 98%

Retinopathy of prematurity in India: incidence, risk factors, outcome and the applicability of current screening criteria

Patel

Shendurnikar

2019

Int J Contemp Pediatr

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“…9,11 There have, however, been several reports of ROP in bigger and more mature babies in India. 16,[19][20][21][22] The lower GA, lower BW as well as the lower proportion of babies weighing >1500 g with ROP in this series are a reflection of improved neonatal care.…”

Section: Resultsmentioning

confidence: 79%

Study of retinopathy of prematurity in high risk infants

Parikh

Patel

Hapani

2018

Int J Contemp Pediatr

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Background: Retinopathy of prematurity is a vaso-proliferative disorder of retina in premature babies. The objective of this study was to study retinopathy of prematurity in premature babies and to study associated risk factors.Methods: Study was a prospective study was conducted among infants in high risk follow up clinic of our department KT Children Hospital, tertiary teaching hospital attached to Government medical college, Rajkot. Sample size of study was conducted on 100 high risk neonates who were brought to high risk follow up clinic at K T children hospital, Rajkot.Results: Out of studied 100 infant, 40% developed ROP, 12% developed stage 1 ROP, 13% developed stage 2 ROP,15% developed stage 3 ROP. Out of 100 cases 40% were ROP positive.15% occurred between 28-30 weeks of gestation. In 31-33 weeks of gestation 82.5%. In 34-36 weeks of gestation 2.5%. 15% of cases between 740-1000 gm of birth weight developed ROP.67.5% between 1000-1500 gm of birth weight developed ROP.15% between 1500-2000 gm of birth weight developed ROP.2.5% between 1500-2000 gm of birth weight developed ROP. 70 newborns received oxygen, 95% of newborns developed ROP. 5% newborns who have not received oxygen developed ROP. In present study there is association of ROP with oxygen therapy. 40 cases had apnea. Out of 40 cases 55% had ROP. Association between apnea and ROP. 21 received blood products.57% of them had ROP. Association between blood transfusion and ROP. 20 received ventilation. 75% of them had ROP. Association between ventilation and ROP. Out of 40 positive newborns there 17 were male and 23 were female. No difference in distribution of ROP in male and female sex. Significant relationship between gestational age, O2 therapy, mechanical ventilation, apnea and blood products. Insignificant relationship between sexes.Conclusions: This study has identified ROP is found to be associated with gestational age, o2 therapy, mechanical ventilation, apnea and blood products.

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“…The incidence and severity of ROP show an inverse relationship with BW and GA, with few cases diagnosed in babies weighing over 1500 g or babies whose GA is >32 weeks at birth. Few reports indicate risk of ROP in mature babies as well [14,[18][19][20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Incidence of retinopathy of prematurity in neonatal intensive care unit in a tertiary care centre in central India

Athale

Jain

2020

Trop j ophthalmol otolaryngol

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Introduction: Retinopathy of Prematurity (ROP) is one of the most common disorders affecting the eyes of premature infants, characterized by abnormal proliferation of retinal blood vessels. In the absence of treatment, it can result in retinal detachment and permanent loss of vision. Advances in neonatal care have resulted in increase in survival rates of very premature infants and consequent increase in incidence of ROP. Purpose: The present study, conducted in a single NICU in a tertiary care centre, estimates the incidence of ROP and evaluates the associated risk factors. Materials and Methods: A retrospective cohort study was performed on premature infants in a tertiary care unit in Central India between February 2018 to July 2019. One hundred and four infants were included in the study based on the following inclusion criteria: Gestational age below 34 weeks, Birth weight below 1700 gms, or babies born with gestational age above 34 weeks or birth weight above 1700 gms, but with any of the following: respiratory distress syndrome, sepsis, intraventricular hemorrhage, blood transfusions or multiple gestation. Follow up was done until disease resolution or until treatment criteria were achieved. Results: A total of 104 infants were evaluated after applying the inclusion criteria. Babies that were screened had mean GA of 30.28 weeks (SD: 2.84, range: 26-36 weeks). Babies with ROP had a mean GA of 28.91 weeks (range: 26-36 weeks, SD: 2.64). The mean Birth weight for the cohort was 1468 g (standard deviation [SD]: 300, range: 830-1870 g). Babies in ROP group had a mean BW of 1278 g (SD: 0.27, range: 830-1726 g). The incidence of ROP of any stage was found to be 25.96%. Babies with a GA of <28 weeks had the highest incidence of ROP (62.8%). A significant association was noted between ROP and oxygen therapy(P<0.01) as well as RDS(P<0.02). Conclusion: This study found incidence of ROP to be 25.96% in the target population and showed respiratory distress and Oxygen therapy to be significant risk factors associated with the disease.

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Retinopathy of prematurity in babies weighing <1800 g; with special reference to babies weighing between 1501 and 1800 g: An experience from a tertiary care hospital in Delhi

Cited by 7 publications

References 10 publications

Retinopathy of prematurity in India: incidence, risk factors, outcome and the applicability of current screening criteria

Retinopathy of prematurity in India: incidence, risk factors, outcome and the applicability of current screening criteria

Study of retinopathy of prematurity in high risk infants

Incidence of retinopathy of prematurity in neonatal intensive care unit in a tertiary care centre in central India

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