Retinal and Orbital Venous Occlusions Treated with Enoxaparin

Abstract

Enoxaparin can be given SC twice a day in patients with retinal or orbital vein occlusions. The occlusions may take from 2 to 19 weeks to open up. Once the vein occlusions are open, the retinal edema, hemorrhage, and the orbital edema can rapidly absorb with visual improvement.

Nonarteritic anterior ischemic optic neuropathy treated with intravenous prostaglandin E1 and steroids

“…A LMWH was used by several of the authors to treat retinal vein occlusions. Enoxaparin was used in a dose of 100 IU/kg every 12 h (15). The patient with the macular star in the present report weighed 60 kg and was given 6000 IU of subcutaneous nadroparin calcium every 12 h, with dramatic improvement in the edema and star after only one week.…”

Nonarteritic anterior ischemic optic neuropathy treated with intravenous prostaglandin E1 and steroids

“…A LMWH was used by several of the authors to treat retinal vein occlusions. Enoxaparin was used in a dose of 100 IU/kg every 12 h (15). The patient with the macular star in the present report weighed 60 kg and was given 6000 IU of subcutaneous nadroparin calcium every 12 h, with dramatic improvement in the edema and star after only one week.…”

An ultra-low-molecular-weight heparin, fondaparinux, to treat retinal vein occlusion

“…As previously reported, enoxaparin was used in ophthalmology to treat 7 cases of RVO and 1 case of an orbital vein occlusion (9). In all 8 cases of venous thrombosis, the thrombus resolved and vision improved in 6 of 8 cases.…”

Nonarteritic anterior ischemic optic neuropathy treated with intravenous prostaglandin E1 and steroids

“…A LMWH was used by several of the authors to treat retinal vein occlusions. Enoxaparin was used in a dose of 100 IU/kg every 12 h (15). The patient with the macular star in the present report weighed 60 kg and was given 6000 IU of subcutaneous nadroparin calcium every 12 h, with dramatic improvement in the edema and star after only one week.…”

An ultra-low-molecular-weight heparin, fondaparinux, to treat retinal vein occlusion

“…As previously reported, enoxaparin was used in ophthalmology to treat 7 cases of RVO and 1 case of an orbital vein occlusion (9). In all 8 cases of venous thrombosis, the thrombus resolved and vision improved in 6 of 8 cases.…”

Nonarteritic anterior ischemic optic neuropathy treated with intravenous prostaglandin E1 and steroids

“…A LMWH was used by several of the authors to treat retinal vein occlusions. Enoxaparin was used in a dose of 100 IU/kg every 12 h (15). The patient with the macular star in the present report weighed 60 kg and was given 6000 IU of subcutaneous nadroparin calcium every 12 h, with dramatic improvement in the edema and star after only one week.…”

An ultra-low-molecular-weight heparin, fondaparinux, to treat retinal vein occlusion

“…As previously reported, enoxaparin was used in ophthalmology to treat 7 cases of RVO and 1 case of an orbital vein occlusion (9). In all 8 cases of venous thrombosis, the thrombus resolved and vision improved in 6 of 8 cases.…”