Retinal and choroidal arterial occlusion in Wegener’s granulomatosis

Iida, Tomohiro; Spaide, Richard F.; Kantor, Jeff

doi:10.1016/s0002-9394(01)01251-x

Cited by 49 publications

(11 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In case 1, choriocapillary nonperfusion was seen in the ICG images. Similar choroidal changes can be seen in Wegner's granulomatosis, where ischemic atrophy of the outer retina by choroidal ischemia has been reported [12]. This similarity also supports the possibility that an immune-mediated complex is the cause of the choroidal changes in dengue fever rather than direct viral invasion.…”

Section: Discussionsupporting

confidence: 75%

Use of Optical Coherence Tomography to Evaluate Visual Acuity and Visual Field Changes in Dengue Fever

Rhee

Han

2014

Korean J Ophthalmol

View full text Add to dashboard Cite

Dengue fever is a viral disease that is transmitted by mosquitoes and affects humans. In rare cases, dengue fever can cause visual impairment, which usually occurs within 1 month after contracting dengue fever and ranges from mild blurring of vision to severe blindness. Visual impairment due to dengue fever can be detected through angiography, retinography, optical coherence tomography (OCT) imaging, electroretinography, event electroencephalography (visually evoked potentials), and visual field analysis. The purpose of this study is to report changes in the eye captured using fluorescein angiography, indocyanine green, and OCT in 3 cases of dengue fever visual impairment associated with consistent visual symptoms and similar retinochoroidopathic changes. The OCT results of the three patients with dengue fever showed thinning of the outer retinal layer and disruption of the inner segment/outer segment (IS/OS) junction. While thinning of the retina outer layer is an irreversible process, disruption of IS/OS junction is reported to be reversible. Follow-up examination of individuals with dengue fever and associated visual impairment should involve the use of OCT to evaluate visual acuity and visual field changes in patients with acute choroidal ischemia.

show abstract

Section: Discussionsupporting

confidence: 75%

Use of Optical Coherence Tomography to Evaluate Visual Acuity and Visual Field Changes in Dengue Fever

Rhee

Han

2014

Korean J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Severe, vision-threatening ocular manifestations can commonly include scleritis, peripheral ulcerative keratitis (PUK), uveitis, and orbital pseudotumor. Rarely, retinal and choroidal involvement in the form of vasculitis or granulomatous lesions have also been reported [4]. …”

Section: Introductionmentioning

confidence: 99%

Cyclophosphamide or Rituximab Treatment of Scleritis and Uveitis for Patients with Granulomatosis with Polyangiitis

Ahmed

Foster

2018

Ophthalmic Res

View full text Add to dashboard Cite

Purpose: Vision-threatening ocular inflammation can be a devastating complication of granulomatosis with polyangiitis (GPA). Here we performed a retrospective observational study to describe the safety and efficacy of treating scleritis and uveitis with either cyclophosphamide or rituximab in GPA. Methods: A chart review of patients diagnosed with GPA-associated scleritis or uveitis, treated with either cyclophosphamide or rituximab as the final therapy at our clinic, was conducted. A total of 1 year of follow-up visits was required for inclusion in the study. Results: Thirteen patients (19 eyes) suffering from GPA-associated scleritis and/or uveitis were identified. As the final therapy, rituximab was administered to 9 patients and cyclophosphamide to 4. Mean duration of follow-up was 55 months (range 16–23 months). Remission was observed in all patients. Three patients had a flare of scleritis after the completion of therapy, and they were restarted on their respective agents. One patient had a flare of retinal vasculitis during rituximab therapy. One patient on cyclophosphamide experienced transient leukopenia. No adverse side effects of rituximab were noted throughout the course of treatment. Conclusions: Cyclophosphamide and rituximab are safe and effective agents for controlling scleritis and uveitis associated with GPA, with eventual progression towards steroid-sparing remission.

show abstract

“…Occlusive retinal vasculitis affecting the retinal arterioles may cause cotton-wool spots representing microinfarcts of the retina. Central retinal artery and branch retinal artery occlusions are also reported in patients with retinal vasculitis [11][12][13][14][15][16][17]. Occlusive periphlebitis can cause retinal edema, intraretinal hemorrhages, and hemorrhagic infarction of the retina.…”

Section: Introductionmentioning

confidence: 99%

A clinical approach to the diagnosis of retinal vasculitis

2009

View full text Add to dashboard Cite

Retinal vasculitis is a sight-threatening inflammatory eye condition that involves the retinal vessels. Detection of retinal vasculitis is made clinically, and is confirmed with the help of fundus fluorescein angiography. Active vascular disease is characterized by exudates around retinal vessels resulting in white sheathing or cuffing of the affected vessels. In this review, a practical approach to the diagnosis of retinal vasculitis is discussed based on ophthalmoscopic and fundus fluorescein angiographic findings.

show abstract

Retinal and choroidal arterial occlusion in Wegener’s granulomatosis

Cited by 49 publications

References 6 publications

Use of Optical Coherence Tomography to Evaluate Visual Acuity and Visual Field Changes in Dengue Fever

Use of Optical Coherence Tomography to Evaluate Visual Acuity and Visual Field Changes in Dengue Fever

Cyclophosphamide or Rituximab Treatment of Scleritis and Uveitis for Patients with Granulomatosis with Polyangiitis

A clinical approach to the diagnosis of retinal vasculitis

Contact Info

Product

Resources

About