Reticulohistiocytoma (Reticulohistiocytic Granuloma)

Montgomery, Hamilton; Polley, Howard F.; Pugh, David G.

doi:10.1001/archderm.1958.01560010063008

Cited by 34 publications

(4 citation statements)

References 8 publications

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“…The clinical and histologic aspects were suggestive, but not characteristic of MRH. Later researchers 9 recognized that the case did not correspond to MRH. The first appropriate and unmistaken case of MRH was described in 1937 1 …”

Section: Historymentioning

confidence: 99%

“…Among the several names used in reference to the disease, the following stand out: nondiabetic cutaneous xanthomatosis, 1 lipoid rheumatism, 2 normocholesteremic xanthomatosis, 3 reticulohistiocytoma, 4–12 multiple skin reticulohistiocytomas with destructive arthritis, 13 reticulomatosis with giant histiocytic cells, 14 reticulohistiocytic granuloma, 15–17 lipoid dermatoarthritis, 18–23 giant‐cell reticulohistiocytosis, 24,25 reticulohistiocytosis with giant cells, 26 giant‐cell histiocytomatosis, 27 giant‐cell histiocytosis, 28 and reticulohistiocytosis 29–32 …”

Section: Definition and Synonymsmentioning

confidence: 99%

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Multicentric Reticulohistiocytosis: A Proliferation of Macrophages With Tropism for Skin and Joints, Part I

Luz

Gaspar

et al. 2007

Skinmed

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The authors present part I of a review of multicentric reticulohistiocytosis, a rare systemic proliferative disease of histiocytes of unknown cause. It is clinically characterized by cutaneous and mucosal nodules and by osteoarticular lesions. The disease occurs in outbreaks that progress in severity, with spontaneous regression, but usually leaving incapacitating arthritis and disfiguring facial lesions. The authors discuss the historical, epidemiologic, and clinical aspects of this disease.

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Section: Historymentioning

confidence: 99%

Section: Definition and Synonymsmentioning

confidence: 99%

Multicentric Reticulohistiocytosis: A Proliferation of Macrophages With Tropism for Skin and Joints, Part I

Luz

Gaspar

et al. 2007

Skinmed

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“…Although Barrow The cause of MR remains an enigma. Various views about the pathogenesis of MR have been described (5,6,8,9,(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32), but none are conclusive.…”

Section: Electron Microscopic Studiesmentioning

confidence: 99%

A Study of Multicentric Reticulohistiocytosis (Lipoid Dermatoarthritis)

Ikezawa

Nakajima

1976

The Journal of Dermatology

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A case of multicentric reticulohistiocytosis is presented, with typical clinical, roentgenologic, and histologic features. The characteristic giant cells were seen in skin nodules, mucosal nodules, synovial and bony lesions of the joints, and tenosynovial cysts. Corticosteroid therapy produced a subjective improvement, but the arthritis mutilans did not improve. Laboratory studies showed iron‐deficiency anemia, hypertriglyceridemia (hyperprebetalipo‐proteinemia), a low response to the unstimulated and stimulated nitroblue tetrazolium test of neutrophils, and a decreased activity in the glucose‐6‐phosphate dehydrogenase of polimorphonuclear leucocytes before corticosteroid therapy. The histochemical examination of the material in the giant cells showed a lipid (a phospholipid and a neutral fat), and a polysaccharide attached to a protein (a muco‐ or glycoprotein). Electron microscopic studies of the giant cells indicated that their cytoplasm contained numerous dense granules clustered in the vicinity of the Golgi apparatus. In some areas the granules appeared to be developing from the Golgi vesicles and cisternas. It seemed likely that the storage material was produced within the giant cells. We also discussed the pathogenesis of this disorder.

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“…Accepted for publication Sept5, 1972. From Veterans Administration Hospital, and the Division of Dermatology, Department of Medicine, University of Tennessee, Memphis.…”

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confidence: 99%