Confluent and reticulated papillomatosis (CRP) is a rare dermatosis of unknown origin characterized by hyperpigmented, confluent papules. The sites of predilection are the neck., inter-mammary area and abdomen (I). Rarely, CRP develops at the other sites, such as the knee, elbow, hand, and antecubital and popliteal fossae (2, 3). We describe two rare cases of CRP that developed at the elbow and popliteal fossae.
CASE REPORTCase I An 18-year-old Korean man presented with an erythematous reticulated scaly plaque in both popliteal fossae. Two weeks earlier, hyperpigmented papules developed in both popliteal fossae and evolved into a reticulated velvety plaque with moderate itching. The skin lesions gradually increased in size and became confluent. At the local hospital, he was treated with an antifungal agent, but the lesions grew further. The physical examination showed a symmetric erythematous reticulated sealy plaque in his popliteal fossae (Fig. 1 ). Routine haematological and biochemical investigations revealed no abnormaliiies. No fungus was found on potassium hydroxide (KOH) examination. His family and pasi histories were non-contributory. Histopathological examination revealed epidermal hyperkeratosis, papiMomatosis. acanthosis, and dermal perivascular sparse lymphocytic infiltration, compatible with CRP. The patient was given methylprednisolone aceponate cream for one week and the lesions faded gradually and cleared within 4 weeks.
Case 2A 17-year-old man presented with erythematous to brownish reticulated patches and plaques on both elbows for one year; these spread to both popliteal fossae and axillae. Physical examination revealed erythematous to brownish patches and plaques in a confluent and reticulated pattern (Fig. 2). K.ÜH preparation and fungal culture of scrapings from the eruptions were negative. The complete blood cell count, erythrocyte sedimentation rate, and liver and kidney function tests were within normal limits. A biopsy specimen taken from the popliteal fossae showed hyperkeratosis. a slightly thickened stratum granulosum. papillomatosis, acanthosis and mild increased pigmentation in the basal layer (Fig. 3), The clinical and histopathological findings were compatible with the diagnosis of Fig. I. Case I. Symmetric erythematous reticulated scaly plaque on the both popliteal fossae.Fig. 2. Case 2. Erythematous to brownish patches and plaques in a confluent and reticulated pattern on the elbow. Acia Derm Venereot 89 ©2(K)9TheAuthore.