Biochemical Pharmacology volume 80, issue 8, P1260-1265 2010 DOI: 10.1016/j.bcp.2010.06.027 View full text
Joseph H. Holthoff, Kellie A. Woodling, Daniel R. Doerge, Samuel T. Burns, Jack A. Hinson, Philip R. Mayeux

Abstract: AbstractOxidant damage from reactive oxygen species (ROS) and reactive nitrogen species (RNS) is a major contributor to the cellular damage seen in numerous types of renal injury. Resveratrol (trans-3, 4′, 5-trihydroxystilbene) is a phytoalexin found naturally in many common food sources. The antioxidant properties of resveratrol are of particular interest because of the fundamental role that oxidant damage plays in numerous forms of kidney injury. To examine whether resveratrol could block damage to the rena…

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