Resurfacing and Reconstruction of the Glans Penis

Palminteri, Enzo; Berdondini, Elisa; Lazzeri, Massimo; Mirri, Francesco; Barbagli, Guido

doi:10.1016/j.eururo.2007.01.047

Cited by 105 publications

(73 citation statements)

References 19 publications

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“…Agrawal et al (4) observed an absence of grade 1-2 penile SCC that extended 1 cm beyond the gross tumor margin; however, 25% of grade 3 lesions were histologically positive at 1 cm (4). In these patients with larger tumors, glansectomy with reconstruction is a better alternative to achieve satisfactory oncological and functional outcomes (27). The reason why age was a negative predictor in LTE patients is not clear.…”

Section: Prior To Matching Subsequent To Matching -------------------mentioning

confidence: 99%

Surgical treatment of primary disease for penile squamous cell carcinoma: A Surveillance, Epidemiology, and End Results database analysis

Zhu

Wang

et al. 2015

Oncology Letters

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Abstract. Current guidelines recommend penile sparing surgery (PSS) for selected penile cancer cases. The present study described the use of PSS in a population-based cohort, and also examined the role of PSS on penile cancer-specific mortality (PCSM). Data from the Surveillance, Epidemiology, and End Results (SEER) database were used to identify individuals that were diagnosed with penile squamous cell carcinoma between 1998 and 2009 and treated with surgery. Patients were sorted into two groups: Local tumor excision (LTE) and partial/total penectomy (PE). Factors associated with the receipt of LTE and PCSM following LTE were examined. In addition, PCSM was compared between LTE and PE following propensity score matching. Of the 1,292 eligible patients, 24.2% underwent LTE. For stage T1 disease, the rates of LTE increased moderately from 29 to 40% over the last decade. Following multivariate analyses, young age, African descent, a tumor size of <3 cm and stage T1 disease were identified to positively influence the receipt of LTE. With a median follow-up period of 55 months, the four-year PCSM rate was 9.8% in patients treated with LTE. Older age, a tumor size of 3-4 cm and regional/distant disease (SEER stage) were significant predictors of PCSM. Furthermore, in matched cohorts with stage T1 disease, the four-year PCSM rates were 8.9 and 10.0% for patients that received LTE or PE, respectively (P=0.93). In conclusion, underuse of PSS is pronounced in the general community with significant age and ethnicity disparities. The current population-based study provides evidence supporting the oncological safety of PSS compared with PE in early-stage disease.

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Section: Prior To Matching Subsequent To Matching -------------------mentioning

confidence: 99%

Surgical treatment of primary disease for penile squamous cell carcinoma: A Surveillance, Epidemiology, and End Results database analysis

Zhu

Wang

et al. 2015

Oncology Letters

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“…With extended follow-up, the results have been promising (39). Glansectomy has been reported with no local recurrences in select cases (38,40,41). Others have performed partial glansectomy and partial penectomy with reconstruction of the glans (38,41,42).…”

Section: Surgery Of the Primary Tumormentioning

confidence: 90%

“…Glansectomy has been reported with no local recurrences in select cases (38,40,41). Others have performed partial glansectomy and partial penectomy with reconstruction of the glans (38,41,42). For results of select studies, please see Table-1. For grade 3 and deeply invasive tumors, particularly those not on the prepuce or glans, partial or total penectomy is the standard therapy (16).…”

Section: Surgery Of the Primary Tumormentioning

confidence: 99%

“…Glans resurfacing has been performed for carcinoma in situ and involves removing all superficial glans and coronal tissue down to the corpus spongiosum. A partial thickness skin graft is then harvested to cover the defect (37,38). "Conservative surgical techniques" consisting of completely removing a tumor guided by preoperative mapping and with frozen section examination of margins preserve uninvolved structures (39).…”

Section: Surgery Of the Primary Tumormentioning

confidence: 99%

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Update in the management of penile cancer

et al. 2009

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Purpose: The management of penile cancer has evolved as less invasive techniques are applied in the treatment of the primary tumor and inguinal lymph nodes. Materials and Methods: Herein we review the literature focusing on advances in the preservation of the phallus as well as less morbid procedures to evaluate and treat the groins. Results: Promising imaging modalities for staging are discussed. New techniques are described and tables provided for penile preservation. We also review the contemporary morbidity of modified surgical forms for evaluation of the inguinal nodes. Conclusions: Advances in surgical technique have made phallic preservation possible in a greater number of primary penile cancers. The groins can be evaluated for metastasis with greater accuracy through new radiologic means as well as with less morbid modified surgical techniques.

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“…They concluded that local disease recurrence rates were lower with the latter treatment (5.3 vs. 27.7%) but there was no significant difference in overall disease survival [43]. Also, patients undergoing penile-preserving therapy (pN+), and those undergoing a wait-and-see policy for the nodal status are at high risk of developing a recurrence [44][45][46][47][48].…”

Section: Partial Penectomymentioning

confidence: 99%

Organ Preservation Surgery for Carcinoma Penis

Yuvaraja

Waigankar

Dharmadhikari

et al. 2016

Indian J Surg Oncol

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Carcinoma of the penis is not uncommon in India. A sizeable number of patients do not report to the doctors in fear of mutilation to the organ and hence subsequently end up with advanced disease. Many patients with T1 or T2 disease when carefully selected are amenable to organ-preserving penile procedures including surgery, topical therapy, laser, and radiation therapy. Identification of appropriate patients and institution of these treatments has been noted to produce oncologically comparable results to extirpative surgeries. In this article, we review the criteria to identify patients qualifying for organ-preserving treatments and also review outcomes with a variety of penile-preserving procedures.

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Resurfacing and Reconstruction of the Glans Penis

Cited by 105 publications

References 19 publications

Surgical treatment of primary disease for penile squamous cell carcinoma: A Surveillance, Epidemiology, and End Results database analysis

Surgical treatment of primary disease for penile squamous cell carcinoma: A Surveillance, Epidemiology, and End Results database analysis

Update in the management of penile cancer

Organ Preservation Surgery for Carcinoma Penis

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