Results of the Universal Neonatal Hearing Screening in a Tertiary Care Hospital in Mexico city

Cruz, Carlos Fabián Martínez; Ramírez-Vargas, Mayra Norma; Themann, Patricia García-Alonso

doi:10.1016/j.ijporl.2020.110412

Cited by 5 publications

(10 citation statements)

References 24 publications

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“…meningitis), trauma or chemotherapy, and caregiver concern. Table 3 shows the number of studies that reported each JCIH risk factor according to WHO region, the number of studies that conducted statistical analysis to determine if that risk factor was associated with hearing loss in their sample, and whether those analyses found significant associations 34–54 …”

Section: Resultsmentioning

confidence: 99%

Prevalence of hearing loss in children living in low‐ and middle‐income countries over the last 10 years: A systematic review

Ganek

Madubueze

Merritt

et al. 2022

Develop Med Child Neuro

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Aim To summarize the literature on the prevalence of pediatric hearing loss in low‐ and middle‐income countries (LMICs). Method A systematic review initially identified 2833 studies, of which 122 met the criteria for inclusion. Eighty‐six of those studies included diagnoses and were included in a meta‐analysis. Results The meta‐analysis indicated a 1% (95% confidence interval = 0.8–2.0) prevalence of childhood hearing loss across LMICs. There was significant heterogeneity between studies and evidence of publication bias. The prevalence of mild and moderate cases of hearing loss was higher than more severe cases and there were fewer cases of mixed hearing loss compared to conductive or sensorineural hearing loss. No differences were identified between the prevalence of unilateral versus bilateral hearing loss or hearing loss according to sex. The quality of the studies, age of participants, and location of data collection may have influenced the results. High variability in the reporting of etiology made the causes of hearing loss unclear. Interpretation The literature indicates that 1% of children in LMICs have hearing losses. However, most studies missed children with acquired hearing loss, which may lead to under‐reporting of global prevalence. This systematic review is an initial step toward developing and implementing population‐appropriate treatment and prevention programs for childhood hearing loss in LMICs. What this paper adds The prevalence of childhood hearing loss in low‐ and middle‐income countries is 1%. Reporting of hearing loss etiology was highly variable.

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Section: Resultsmentioning

confidence: 99%

Prevalence of hearing loss in children living in low‐ and middle‐income countries over the last 10 years: A systematic review

Ganek

Madubueze

Merritt

et al. 2022

Develop Med Child Neuro

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“…16 En México la prevalencia de pérdida auditiva significativa se estima en 2.2 por cada 10,000 recién nacidos, de los cuales 65% corresponde a sordera neurosensorial y 35% a sordera conductiva. 17,18 El principal objetivo del TANU es la detección de trastornos auditivos congénitos permanentes, principalmente aquellos severos o profundos, cuya identificación y tratamiento oportuno mejoran la adquisición del lenguaje, el desarrollo cognitivo y psicosocial. 3,18 Las metas del TANU son lograr una evaluación audiológica universal durante el primer mes de vida, confirmar casos de hipoacusia antes del tercer mes e iniciar el tratamiento antes de los seis meses.…”

Section: Tamizaje Auditivounclassified

“…16 En México el equipo del Dr. Pedro Berruecos en el Hospital General de México fue pionero en la implementación del TANU; desde 2009 se han realizado esfuerzos para ampliarlo al resto de instituciones, adquiriéndose equipos y capacitándose personal de salud; sin embargo, la cobertura nacional de este programa permanece muy por debajo de la meta de 95% propuesta por el Comité Internacional sobre Pruebas Auditivas Infantiles (JCIH), siendo en 2012 de 57% de los recién nacidos. 3,17 Las técnicas de tamizaje auditivo más utilizadas alrededor del mundo son: 16,17 Alrededor de 4% de los RN tamizados con PEATC y 15% con EOA, no pasan el tamiz auditivo y requieren una segunda prueba de tamizaje. Los RN con dos pruebas alteradas deberán ser referidos con un audiólogo para pruebas adicionales.…”

Section: Tamizaje Auditivounclassified

“…Las intervenciones tempranas incluyen el uso de aparatos auditivos, implantes cocleares, educación familiar y seguimiento audiológico. 17 En México, de acuerdo a las guías de práctica clínica de hipoacusia neurosensorial, a los RN sin respuesta en la primera prueba se les realiza una segunda evaluación entre las 2 y 8 semanas siguientes, si persisten las alteraciones son evaluados por el audiólogo con PPATC antes de los tres meses. 19 Un reto para los programas de TANU es la pérdida de pacientes durante el seguimiento de los casos sospechosos, de acuerdo a estudios en EUA hasta 1/3 de los RN no regresen a la valoración por el audiólogo o una segunda prueba auditiva.…”

Section: Tamizaje Auditivounclassified

“…De acuerdo a un estudio realizado en México en el Instituto Nacional de Perinatología (INPer) 30% de los RN con una prueba de tamizaje alterada no regresaron a la segunda prueba y casi la mitad de los RN con 2 pruebas alteradas (EOA) no acudieron a la prueba confirmatoria (PEATC). 17 Algunas de las barreras para mejorar la cobertura y la eficacia de estos programas son recursos de salud limitados, escasez de personal calificado (médicos especialistas en audiología, otorrinolaringología, otoneurología y foniatría y licenciados en terapia de la comunicación humana), así como falta de concientización en la población general sobre la importancia de este programa. 18…”

Section: Tamizaje Auditivounclassified

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El Tamiz neonatal integral y su impacto en el recién nacido

Flores-Robles¹,

Ramírez-Vargas²,

López-Navarrete³

2023

Revista CONAMED

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Los programas de tamizaje neonatal (TN) representan una de las estrategias de salud pública más efectivas en México y el mundo. Su objetivo es identificar recién nacidos asintomáticos con condiciones que pueden causar enfermedad, discapacidad o incluso la muerte, para que puedan recibir un tratamiento oportuno, mejorar su calidad de vida y reducir su morbimortalidad. En México el primer programa nacional de tamizaje metabólico empezó a operar en 1989 y en las últimas dos décadas se han añadido a la ley general de salud el tamizaje auditivo universal, el tamiz oftalmológico y recientemente el tamizaje cardiaco. Estos programas han logrado reducir discapacidad y muerte en miles de niños mexicanos; sin embargo, aún es necesario incrementar esfuerzos y asignar mayores recursos humanos y económicos a estos programas para su consolidación.

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High prevalence of syndromic hearing loss in Mexican children undergoing cochlear implantation

Rodriguez‐Valero,

Pastolero,

Redfield

et al. 2024

Laryngoscope Investig Oto

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ObjectiveStudies evaluating genetic sensorineural hearing loss (SNHL) in Hispanic and Latino populations using genomic technologies are lacking. Recent data has shown that Hispanic and Latino children display lower genetic diagnostic rates despite similar prevalence rates of SNHL to their Asian and White counterparts, thus negatively affecting their clinical care. Our objective was to determine the genetic contribution to SNHL in a population of Mexican children undergoing evaluation for cochlear implantation.MethodsPediatric patients from Mexico with severe to profound SNHL undergoing evaluation for cochlear implantation were recruited. Exome sequencing (ES) or hearing loss gene panel testing was performed. Variant pathogenicity was established in accordance to criteria established by the American College of Medical Genetics, and variants of interest were clinically confirmed via CLIA certified laboratory.ResultsGenetic evaluation was completed for 30 Mexican children with severe to profound SNHL. A genetic cause was identified for 47% (14) of probands, and 7% (2) probands had an inconclusive result. Of the diagnoses, 10 (71%) were syndromic or likely syndromic, and 4 (29%) were nonsyndromic. Eight probands (80% of all syndromic diagnoses) were diagnosed with a syndromic form of hearing loss that mimics a nonsyndromic clinical presentation at a young age and so could not be suspected based on clinical evaluation alone without genetic testing.ConclusionThis is the largest study to date to use comprehensive genomic testing for the evaluation of Mexican children with severe to profound SNHL. A significant proportion of children in this cohort were diagnosed with syndromic hearing loss. Future study in a larger cohort of Mexican children with varying degrees of hearing loss is required to improve the efficacy of genetic testing and timely medical intervention within these ethnically diverse populations.Level of evidenceLevel 4 (cohort study).

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Results of the Universal Neonatal Hearing Screening in a Tertiary Care Hospital in Mexico city

Cited by 5 publications

References 24 publications

Prevalence of hearing loss in children living in low‐ and middle‐income countries over the last 10 years: A systematic review

Prevalence of hearing loss in children living in low‐ and middle‐income countries over the last 10 years: A systematic review

El Tamiz neonatal integral y su impacto en el recién nacido

High prevalence of syndromic hearing loss in Mexican children undergoing cochlear implantation

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