Results of Pediatric Cardiac Transplantation - Long-Term Results of a 15-Year Experience

Abstract

Pediatric heart transplantation is a curative treatment for DCM and CHD with excellent clinical mid-term results. However, further follow-up is necessary to evaluate long-term side effects of immunosuppressants. Donor shortage remains a problem.

Renal Transplantation After Previous Pediatric Heart Transplantation

“…For the latter cohort, Time 0 is defined as 11.0 years after primary heart Tx. freedom from acute rejection over 5 years, 25 and Ͼ90% patients remained free from severe renal dysfunction after 8 years. 26 Although there are limited data on "renal-sparing" immunosuppressant regimens in children, caution should be exercised in risking cardiac allograft rejection at the cost of renal preservation.…”

Outcome of shared care for pediatric cardiac transplantation between two nations with different health care systems

“…[1][2][3][4][5][6][7] This may reflect the close monitoring of drug levels, early direct referral for symptoms, and the shared care pathway we use for monitoring patients until transition. Patients who developed late rejection were treated primarily in the referral center with advice from the transplant center.…”

Historical review and perspectives in pediatric transplantation

“…Results of a 15-year experience with 55 pediatric (aged <18 years) heart transplant patients were reported from Germany [52 ]. Operative mortality rate was 6.8%, due to primary graft failure.…”