Restrospective reappraisal of the prognostic classification of spitzoid melanocytic neoplasms after BRAF and NRAS mutation characterisation: a single institution experience
Irene Moysset,
Natalia Castrejon,
Adriana Garcia‐Herrera
et al.
Abstract:AimsThe current WHO classification of melanocytic tumours excludes neoplasms showing BRAF or NRAS mutations from the Spitz category. This study aimed to review and reclassify atypical melanocytic tumours with spitzoid morphological features diagnosed between 2009 and 2021 in our hospital after expanding the molecular profile, including BRAF and NRAS mutations in all cases.Methods and resultsA total of 71 neoplasms showing spitzoid features (Spitz‐like) and atypia were included. The risk of progression of tumou… Show more
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