Restoration of Suppressor T-Cell Functions in Children With AIDS Following Intravenous Gamma Globulin Treatment

Superior effect of intravenous anti‐D compared with IV gammaglobulin in the treatment of HIV‐thrombocytopenia: Results of a small, randomized prospective comparison

“…The lack of significant %CD4 decline and absence of opportunistic infections are in agreement with our retrospective evaluation of 18 HIV-TP patients on maintenance anti-D therapy followed for a median of 4.8 years [15]. Similarly, there is a large experience with monthly administration of 400 mg/kg of IVIG with beneficial clinical and immunological effects in children with HIV infection [25][26][27][28].…”

Superior effect of intravenous anti‐D compared with IV gammaglobulin in the treatment of HIV‐thrombocytopenia: Results of a small, randomized prospective comparison

“…The lack of significant %CD4 decline and absence of opportunistic infections are in agreement with our retrospective evaluation of 18 HIV-TP patients on maintenance anti-D therapy followed for a median of 4.8 years [15]. Similarly, there is a large experience with monthly administration of 400 mg/kg of IVIG with beneficial clinical and immunological effects in children with HIV infection [25][26][27][28].…”

Lymphocyte Proliferation in AIDS-Related Complex/Walter-Reed 5 Patients: Response to Herpes Simplex Virus and Tuberculin Antigen and Mitogen during Intravenous Immunoglobulin Treatment

“…This effect might be explained by specific antibodies sub stituting the inability of AIDS patients to develop humoral immunity. Other observations tend to explain the effect of IVIG by inhibition of polyclonal B cell proliferation [9] and thereby probably protection from autoimmune phenomena [2,3], The present study, aimed at the evaluation of the effect of IVIG treatment in adults, showed some amelioration in clinical symptoms [10, this issue], but failed to demonstrate a therapeutic influence on immunological parameters in general. The possible reconstitution of immune response as measured by lymphocyte functions on several levels under IVIG treatment was studied in detail.…”

“…number of bacterial infections following treatment [8,9]. This effect might be explained by specific antibodies sub stituting the inability of AIDS patients to develop humoral immunity.…”

Usefulness of a low‐dose intravenous immunoglobulin regimen for the treatment of thrombocytopenia associated with AIDS

“…Using IVIg in the supportive care of children with nonthrombocytopenic AIDS, immunosuppression is not seen [52], and in Ig deficient cases, it reduces the infection rate [26]. Despite reports associating infection with IVIg [53], blockade of the Fc receptor function in ITP, and in vitro changes in Ig production, circulating lymphocytes, and T4:T8 ratio [54][55][56], it seems that IVIg is a safe approach for HIV-Thr of AIDS.…”

Superior effect of intravenous anti‐D compared with IV gammaglobulin in the treatment of HIV‐thrombocytopenia: Results of a small, randomized prospective comparison

“…The lack of significant %CD4 decline and absence of opportunistic infections are in agreement with our retrospective evaluation of 18 HIV-TP patients on maintenance anti-D therapy followed for a median of 4.8 years [15]. Similarly, there is a large experience with monthly administration of 400 mg/kg of IVIG with beneficial clinical and immunological effects in children with HIV infection [25][26][27][28].…”

Lymphocyte Proliferation in AIDS-Related Complex/Walter-Reed 5 Patients: Response to Herpes Simplex Virus and Tuberculin Antigen and Mitogen during Intravenous Immunoglobulin Treatment

“…This effect might be explained by specific antibodies sub stituting the inability of AIDS patients to develop humoral immunity. Other observations tend to explain the effect of IVIG by inhibition of polyclonal B cell proliferation [9] and thereby probably protection from autoimmune phenomena [2,3], The present study, aimed at the evaluation of the effect of IVIG treatment in adults, showed some amelioration in clinical symptoms [10, this issue], but failed to demonstrate a therapeutic influence on immunological parameters in general. The possible reconstitution of immune response as measured by lymphocyte functions on several levels under IVIG treatment was studied in detail.…”

“…number of bacterial infections following treatment [8,9]. This effect might be explained by specific antibodies sub stituting the inability of AIDS patients to develop humoral immunity.…”

Usefulness of a low‐dose intravenous immunoglobulin regimen for the treatment of thrombocytopenia associated with AIDS

“…Using IVIg in the supportive care of children with nonthrombocytopenic AIDS, immunosuppression is not seen [52], and in Ig deficient cases, it reduces the infection rate [26]. Despite reports associating infection with IVIg [53], blockade of the Fc receptor function in ITP, and in vitro changes in Ig production, circulating lymphocytes, and T4:T8 ratio [54][55][56], it seems that IVIg is a safe approach for HIV-Thr of AIDS.…”

Superior effect of intravenous anti‐D compared with IV gammaglobulin in the treatment of HIV‐thrombocytopenia: Results of a small, randomized prospective comparison

“…The lack of significant %CD4 decline and absence of opportunistic infections are in agreement with our retrospective evaluation of 18 HIV-TP patients on maintenance anti-D therapy followed for a median of 4.8 years [15]. Similarly, there is a large experience with monthly administration of 400 mg/kg of IVIG with beneficial clinical and immunological effects in children with HIV infection [25][26][27][28].…”

Lymphocyte Proliferation in AIDS-Related Complex/Walter-Reed 5 Patients: Response to Herpes Simplex Virus and Tuberculin Antigen and Mitogen during Intravenous Immunoglobulin Treatment

“…This effect might be explained by specific antibodies sub stituting the inability of AIDS patients to develop humoral immunity. Other observations tend to explain the effect of IVIG by inhibition of polyclonal B cell proliferation [9] and thereby probably protection from autoimmune phenomena [2,3], The present study, aimed at the evaluation of the effect of IVIG treatment in adults, showed some amelioration in clinical symptoms [10, this issue], but failed to demonstrate a therapeutic influence on immunological parameters in general. The possible reconstitution of immune response as measured by lymphocyte functions on several levels under IVIG treatment was studied in detail.…”

“…number of bacterial infections following treatment [8,9]. This effect might be explained by specific antibodies sub stituting the inability of AIDS patients to develop humoral immunity.…”

Usefulness of a low‐dose intravenous immunoglobulin regimen for the treatment of thrombocytopenia associated with AIDS

“…Using IVIg in the supportive care of children with nonthrombocytopenic AIDS, immunosuppression is not seen [52], and in Ig deficient cases, it reduces the infection rate [26]. Despite reports associating infection with IVIg [53], blockade of the Fc receptor function in ITP, and in vitro changes in Ig production, circulating lymphocytes, and T4:T8 ratio [54][55][56], it seems that IVIg is a safe approach for HIV-Thr of AIDS.…”