Responsiveness of Choroidal Neovascular Membranes in Patients With R345W Mutation in Fibulin 3 (Doyne Honeycomb Retinal Dystrophy) to Anti–Vascular Endothelial Growth Factor Therapy

EFEMP1 Overexpression Contributes to Neovascularization in Age-Related Macular Degeneration

“…may participate in the proangiogenesis process induced by fibulin-3. These results are also consistent with the findings in a previous study whereby CNV cases with R345W mutation in EFEMP1 were sensitive to anti-VEGF treatment (Sohn et al, 2011).…”

EFEMP1 Overexpression Contributes to Neovascularization in Age-Related Macular Degeneration

“…may participate in the proangiogenesis process induced by fibulin-3. These results are also consistent with the findings in a previous study whereby CNV cases with R345W mutation in EFEMP1 were sensitive to anti-VEGF treatment (Sohn et al, 2011).…”

Clinical outcomes of treated macular neovascularisation secondary to inherited retinal diseases: a literature review

“…This condition is characterised by extensive drusen and can be complicated by MNV in advanced stages, which has been successfully treated with intravitreal bevacizumab, 42 except one case where the VA continued to reduce despite anatomical improvement. 40 …”

Familial dominant drusen (Malattia leventinese / Doyne honeycomb retinal dystrophy)

“…Currently, there are no genetic or targeted therapies to correct the underlying genetic mutation in DHRD. Typically, patients with Doyne honeycomb retinal dystrophy are managed conservatively with observation, unless a choroidal neovascularisation develops [13] .…”

EFEMP1 Overexpression Contributes to Neovascularization in Age-Related Macular Degeneration

“…may participate in the proangiogenesis process induced by fibulin-3. These results are also consistent with the findings in a previous study whereby CNV cases with R345W mutation in EFEMP1 were sensitive to anti-VEGF treatment (Sohn et al, 2011).…”

Clinical outcomes of treated macular neovascularisation secondary to inherited retinal diseases: a literature review

“…This condition is characterised by extensive drusen and can be complicated by MNV in advanced stages, which has been successfully treated with intravitreal bevacizumab, 42 except one case where the VA continued to reduce despite anatomical improvement. 40 …”

Familial dominant drusen (Malattia leventinese / Doyne honeycomb retinal dystrophy)

“…Currently, there are no genetic or targeted therapies to correct the underlying genetic mutation in DHRD. Typically, patients with Doyne honeycomb retinal dystrophy are managed conservatively with observation, unless a choroidal neovascularisation develops [13] .…”

EFEMP1 Overexpression Contributes to Neovascularization in Age-Related Macular Degeneration

“…may participate in the proangiogenesis process induced by fibulin-3. These results are also consistent with the findings in a previous study whereby CNV cases with R345W mutation in EFEMP1 were sensitive to anti-VEGF treatment (Sohn et al, 2011).…”

Clinical outcomes of treated macular neovascularisation secondary to inherited retinal diseases: a literature review

“…This condition is characterised by extensive drusen and can be complicated by MNV in advanced stages, which has been successfully treated with intravitreal bevacizumab, 42 except one case where the VA continued to reduce despite anatomical improvement. 40 …”

Familial dominant drusen (Malattia leventinese / Doyne honeycomb retinal dystrophy)

“…Currently, there are no genetic or targeted therapies to correct the underlying genetic mutation in DHRD. Typically, patients with Doyne honeycomb retinal dystrophy are managed conservatively with observation, unless a choroidal neovascularisation develops [13] .…”