Responses of mycosis fungoides to intensive external treatment with nitrogen mustard

Clinical potential of mechlorethamine gel for the topical treatment of mycosis fungoides-type cutaneous T-cell lymphoma: a review on current efficacy and safety data

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Remissions of Mycosis Fungoides Induced by Nitrogen Mustard (HN 2 )

“…Rapid remission of disease seems to be associated with this reaction to HN2 [9], but it can be a serious complication to topical therapy. Nevertheless, improvement of the disease by topical HN2 therapy seems to occur as well in patients who never develop such reactions [14]. Van Scott and K almanson [13] induced specific immunologic tolerance to HN2 prior to topical treatment and found that none of 12 patients became sensitized.…”