Response Surface Modelling of Electrosprayed Polyacrylonitrile Nanoparticle Size

Abstract

Electrospraying (electrohydrodynamic spraying) is a method of liquid atomization by electrical forces. Spraying solutions or suspensions allow production of fine particles, down to nanometer size. These particles are interesting for a wide variety of applications, thanks to their unprecedented chemical and physical behaviour in comparison to their bulk form. Knowledge of the particle size in powders is important in many studies employing nanoparticles. In this paper, the effect of some process parameters on the size of electrosprayed polyacrylonitrile particles is presented in the form of response surface model. The model is achieved by employing a factorial design to evaluate the influence of parameters on the polyacrylonitrile nanoparticle size and response surface methodology. Four electrospraying parameters, namely, applied voltage, electrospraying solution concentration, flow rate, and syringe needle diameter were considered.

Overlooked Promising Green Features of Electrospun Cellulose-Based Fibers in Lithium-Ion Batteries

“…Cellulose nanofiber possesses high mechanical strength, thermal stability, functionalization possibility, and small thermal expansion . Correspondingly, it has been regarded as a latent matrix for numerous applications, such as drug delivery, energy storage, optoelectronic conversion, filtration, and many more. − In accordance with the literature, cellulose nanofiber could be obtained through chemical, mechanical, oxidation, and biological methods. The chemical approach is based on acid digestion in which cellulose nanofibers are obtained by destroying amorphous areas of fibers .…”

PCL/Fe3O4 magnetic electrospun yarn composites as a novel nanomaterial for biomedical applications

“…The observed significant difference between the average diameters of the electrospun fibers in various structures might result from various electrospinning sets up used for fabrication of the aforementioned nanofibrous structures. It seems that the electrospinning electric field formed in the membrane fabrication setup has more affected the polymeric jet in electrospinning distance compared to that of the yarn fabrication setup (Khademolqorani, Zeinal Hamadani, & Tavanai, 2014).…”

Application of Electrosprayed Nanoparticles as Targeted Drug Delivery Systems: A Mini Review

“…A constant flow rate is required to sustain the liquid flow from this meniscus. The sizes of particles and their distribution are influenced by the applied voltage, solution concentration, flow rate, and syringe needle diameter, along with material characteristics [15]. Besides numerous reported applications for the monoaxial electrosprayed NPs, the fabrication of core-shell NPs has received wide attention for targeted drug delivery systems.…”

“…These approaches are further subdivided depending on the operation, response condition, and procedures. Optical lithography, E-beam lithography, scanning probe lithography, atomic layer deposition, sol-gel nanofabrication, molecular selfassembly, vapor-phase deposition, mechanical attrition, and specifically electro-hydrodynamic atomization or electrospray are some of the methods used to synthesize nanoparticles [15]. According to the statistical analysis in Figure 1, the number of publications involving 'electrospray nanoparticles applied in drug delivery systems has rapidly increased, which indicates that the research on electrospray nanoparticles is in full swing during the past decade.…”