Response of the matrix metalloproteinase system of the chicken ovary to prolactin treatment

Hrabia, Anna; Wolak, Dominika; Sechman, Andrzej

doi:10.1016/j.theriogenology.2021.04.002

Cited by 6 publications

(7 citation statements)

References 34 publications

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“…PRL also plays an important role in reproduction of nonmammalian species. In chickens, PRL participates in the mechanisms orchestrating ECM turnover during ovarian follicular development in the hen ( Gallus domesticus ) ovary by regulating the transcription, translation, and/or activity of some components of the MMP system ( Hrabia et al, 2021 ). Similarly, in fish, PRL has been shown to play a role in reproductive development and sexual maturity.…”

Section: Discussionmentioning

confidence: 99%

Brain and Pituitary Transcriptome Analyses Reveal the Differential Regulation of Reproduction-Related LncRNAs and mRNAs in Cynoglossus semilaevis

et al. 2021

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Long noncoding RNAs (lncRNAs) have been identified to be involved in half-smooth tongue sole (Cynoglossus semilaevis) reproduction. However, studies of their roles in reproduction have focused mainly on the ovary, and their expression patterns and potential roles in the brain and pituitary are unclear. Thus, to explore the mRNAs and lncRNAs that are closely associated with reproduction in the brain and pituitary, we collected tongue sole brain and pituitary tissues at three stages for RNA sequencing (RNA-seq), the 5,135 and 5,630 differentially expressed (DE) mRNAs and 378 and 532 DE lncRNAs were identified in the brain and pituitary, respectively. The RNA-seq results were verified by RT-qPCR. Moreover, enrichment analyses were performed to analyze the functions of DE mRNAs and lncRNAs. Interestingly, their involvement in pathways related to metabolism, signal transduction and endocrine signaling was revealed. LncRNA-target gene interaction networks were constructed based on antisense, cis and trans regulatory mechanisms. Moreover, we constructed competing endogenous RNA (ceRNA) networks. In summary, this study provides mRNA and lncRNA expression profiles in the brain and pituitary to understand the molecular mechanisms regulating tongue sole reproduction.

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Section: Discussionmentioning

confidence: 99%

Brain and Pituitary Transcriptome Analyses Reveal the Differential Regulation of Reproduction-Related LncRNAs and mRNAs in Cynoglossus semilaevis

et al. 2021

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“…In follicles of the mature hen ovary, the expression of MMP-2, MMP-3, MMP-9, MMP-10, and MMP-13 mRNAs and/or proteins as well as gelatinase (MMP-2 and MMP-9) activities increase along with follicular maturation [ 36 , 38 , 39 , 40 , 41 , 42 , 43 ]. These correlative findings suggest the engagement of some MMPs in the turnover of the ECM/follicular wall structure during the final stage of ovarian follicle maturation.…”

Section: Mmp Roles In Follicle Development and Atresiamentioning

confidence: 99%

“…These correlative findings suggest the engagement of some MMPs in the turnover of the ECM/follicular wall structure during the final stage of ovarian follicle maturation. Moreover, transcript and/or protein abundances of MMP-2, MMP-7, MMP-9, MMP-10, and MMP-13 as well as of TIMP-2 and TIMP-3 differ between white and yellowish follicles and the small yellow follicles just recruited into the preovulatory hierarchy [ 39 , 40 ]. Furthermore, atresia of white follicles is accompanied by an increase in MMP-2 and MMP-9 activities [ 39 ].…”

Section: Mmp Roles In Follicle Development and Atresiamentioning

confidence: 99%

“…Importantly, all the MMPs detected are expressed more strongly in the theca than in the granulosa layer. In the latter, MMPs are at a very low level, barely detectable (e.g., MMP-9, MMP-13) or not detectable (e.g., MMP-7) [ 38 , 39 , 40 , 41 , 42 , 43 ]. These findings are consistent with the presence of fibroblasts, which are a known source of MMPs in the theca layer.…”

Section: Mmp Roles In Follicle Development and Atresiamentioning

confidence: 99%

“…The author’s recent results [ 40 ] suggest that prolactin is another actor in the hen ovary implicated in the orchestration of ECM turnover and/or cell functions. Treatment of egg-laying hens with recombinant chicken prolactin induces alterations in the mRNA expression of MMP-2 , MMP-7 , MMP-9 , MMP-10 , MMP-13 , TIMP-2 , and TIMP-3 , as well as in the protein abundance of gelatinases in different ovarian follicles.…”

Section: Mmp Regulation In the Avian Reproductive Systemmentioning

confidence: 99%

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Matrix Metalloproteinases (MMPs) and Inhibitors of MMPs in the Avian Reproductive System: An Overview

Hrabia

2021

IJMS

Self Cite

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Many matrix metalloproteinases (MMPs) are produced in the mammalian reproductive system and participate in the regulation of its functions. In birds, the limited information available thus far indicates that MMPs are significant regulators of avian ovarian and oviductal functions, too. Some MMPs and inhibitors of MMPs are present in the hen reproductive tissues and their abundances and/or activities change according to the physiological state. The intraovarian role of MMPs likely includes the remodeling of the extracellular matrix (ECM) during folliculogenesis, follicle atresia, and postovulatory regression. In the oviduct, MMPs are also involved in ECM turnover during oviduct development and regression. This study provides a review of the current knowledge on the presence, activity, and regulation of MMPs in the female reproductive system of birds.

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TGF-β1 induces type I collagen deposition in granulosa cells via the AKT/GSK-3β signaling pathway-mediated MMP1 down-regulation

Shen

Wang

Zhao

et al. 2022

Reproductive Biology

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Response of the matrix metalloproteinase system of the chicken ovary to prolactin treatment

Cited by 6 publications

References 34 publications

Brain and Pituitary Transcriptome Analyses Reveal the Differential Regulation of Reproduction-Related LncRNAs and mRNAs in Cynoglossus semilaevis

Brain and Pituitary Transcriptome Analyses Reveal the Differential Regulation of Reproduction-Related LncRNAs and mRNAs in Cynoglossus semilaevis

Matrix Metalloproteinases (MMPs) and Inhibitors of MMPs in the Avian Reproductive System: An Overview

TGF-β1 induces type I collagen deposition in granulosa cells via the AKT/GSK-3β signaling pathway-mediated MMP1 down-regulation

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