Respiratory Tract Diseases That May Be Mistaken for Infection

Kotloff, Robert M.; Dickey, Burton F.; Vander, Nicholas

doi:10.1007/978-1-4939-9034-4_21

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2024

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“…Recent studies have provided valuable insights into the mechanisms of TRALI, which have implications for its diagnosis and managemen [10]. For instance, it has been suggested that TRALI may be triggered by the interaction between donor antibodies and recipient leukocytes, leading to the activation of the recipient's neutrophils and the release of inflammatory mediators [4].…”

Section: Discussionmentioning

confidence: 99%

Acute Lung Injury Associated with Blood Transfusion in a Hysterectomy Patient: A Case Report

Bielinskyi,

Halandzhii,

Dashchenko

et al. 2024

Galician med. j.

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This case report presents a case of transfusion-related acute lung injury (TRALI) in a 50-year-old female patient who underwent total hysterectomy due to multiple fibromyomas. The patient developed dyspnea, heart palpitations, and fatigue postoperatively, with SpO2 dropping to 61%. Despite initially suspecting pulmonary embolism, the normal D-dimer level and characteristic changes observed on X-ray facilitated the diagnosis of TRALI. The patient was successfully treated with oxygen supplementation, intravenous corticosteroids, and thromboembolism prophylaxis, resulting in complete recovery. This case underscores the importance of considering TRALI in the differential diagnosis when patients exhibit respiratory distress following transfusion.

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Section: Discussionmentioning

confidence: 99%