Respiratory infections in elderly people: Viral role in a resident population of elderly care centers in Lisbon, winter 2013–2014

Chasqueira, Maria Jesus; Paixão, Paulo; Rodrigues, Maria Lúcia; Piedade, Cátia; Caires, Iolanda; Palmeiro, Teresa; Botelho, Maria Amália; Santos, Madalena; Curran, Martin D.; Guiomar, Raquel; Pechirra, Pedro; Costa, Inês; Papoila, Ana Luísa; Alves, Marta; Neuparth, Nuno

doi:10.1016/j.ijid.2018.01.012

Cited by 17 publications

(16 citation statements)

References 23 publications

(29 reference statements)

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“…Similar to other studies, 17,20 influenza viruses were commonly encountered in LTCF residents and accounted for 32% of detections over the 3-year study period. Human metapneumovirus, CoV, and RSV were also common.…”

Section: Discussionsupporting

confidence: 86%

Evaluation of Viruses Associated With Acute Respiratory Infections in Long-Term Care Facilities Using a Novel Method: Wisconsin, 2016‒2019

Checovich¹,

Barlow²,

Shult³

et al. 2020

Journal of the American Medical Directors Association

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Keywords:Long-term care acute respiratory infection rapid influenza diagnostic testing influenza a b s t r a c t Residents of long-term care facilities (LCTFs) have high morbidity and mortality associated with acute respiratory infections (ARIs). Limited information exists on the virology of ARI in LTCFs, where virological testing is reactive. We report on findings of a surveillance feasibility substudy from a larger prospective trial of introducing rapid influenza diagnostic testing (RIDT) at 10 Wisconsin LTCFs. Any resident with symptoms consistent with ARI had a nasal swab specimen collected for RIDT by staff. Following RIDT, the residual swab was placed into viral transport medium and tested for influenza using Reverse transcription polymerase chain reaction, and for 20 pathogens using a multiplex polymerase chain reaction respiratory pathogen panel. Numbers of viruses in each of 7 categories (influenza A, influenza B, coronaviruses, human metapneumovirus, parainfluenza, respiratory syncytial virus, and rhinovirus/enterovirus) across the 3 years were compared using c 2 . Totals of 160, 215, and 122 specimens were collected

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Section: Discussionsupporting

confidence: 86%

Evaluation of Viruses Associated With Acute Respiratory Infections in Long-Term Care Facilities Using a Novel Method: Wisconsin, 2016‒2019

Checovich¹,

Barlow²,

Shult³

et al. 2020

Journal of the American Medical Directors Association

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“…Nucleic acid extraction was performed with the same commercial kit used in the study of Wang et al [13], who analized the respiratory virome of healthy and severe acute respiratory infection children through metagenomic analysis. We used "in-house" real-time PCR and RT-PCR techniques that were tested and validated long before [16].…”

Section: Discussionmentioning

confidence: 99%

“…"In house" real-time Taqman PCR and RT-PCR techniques, detailed elsewhere [16], were used for the detection of DNA and RNA respiratory viruses: adenovirus, human bocavirus (HBoV), influenza virus A/B, respiratory syncytial virus (RSV), human parainfluenza virus (HPIV) types 1/3 and 2/4, human enterovirus (HEV), human rhinovirus (HRV), human metapneumovirus (HMPV), human coronavirus (HCoV) group 1 (229E, NL63) and 2 (OC43, HKU1).…”

Section: Laboratory Methodsmentioning

confidence: 99%

Respiratory viruses in mechanically ventilated patients: a pilot study

et al. 2020

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Background: Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with acute lower respiratory infections. The aim of this study was to evaluate the presence of respiratory viruses in the lower airways of individuals undergoing invasive mechanical ventilation, with and without acute lower respiratory infection (respectively WRI and WORI groups). Methods: We studied 44 mini-bronchoalveolar lavage samples (collected with a double catheter, Combicath® kit) from patients with mean age in the seventh decade, 20 from WORI group and 24 from WRI group, who were hospitalized for acute respiratory failure in Intensive Care Units of two hospitals in the Lisbon area. Real-time PCR was applied to verify analyse the presence of 15 common respiratory viruses (adenovirus, human bocavirus, influenza virus A and B, repiratory syncytial virus, human parainfluenza virus types 1, 2, 3 and 4, human enterovirus, human rhinovirus, human metapneumovirus, human coronavirus group 1 (229E, NL63) and 2 (OC43, HKU1). Results: Respiratory viruses were detected in six of the 20 patients in the WORI group: influenza AH3 (n = 2), parainfluenza virus 1/3 (n = 2), human rhinovirus (n = 2), respiratory syncytial virus (n = 1) and human metapneumovirus (n = 1). In the WRI group, respiratory viruses were detected in 12 of the 24 patients: influenza AH3 (n = 3), human rhinovirus (n = 3), respiratory syncytial virus (n = 3), human metapneumovirus (n = 3), human bocavirus (n = 2) and human enterovirus (n = 1). Simultaneous detection of two viruses was recorded in two samples in both groups. Conclusions: The results of this study suggest the presence of common respiratory viruses in the lower respiratory tract without causing symptomatic infection, even in carefully collected lower samples. This may have important implications on the interpretation of the results on the diagnostic setting.

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“…Auf der Suche nach Infektionserregern ambulant erworbener Pneumonien (CAP) bei älteren Menschen untersuchten Forscher aus Lissabon zwischen November 2013 und April 2014 163 Patienten [13]. Bei 113 Krankheitsepisoden wurden positive Tests in der PCR-Untersuchung gefunden: am häu gsten Rhinoviren und In uenza, danach Boca-, Corona-und Metapneumo-, Parain uenza-Virus und auch Legionellen.…”

Section: Respiratorische Viren Parainfluenzaunclassified

“…Bei 113 Krankheitsepisoden wurden positive Tests in der PCR-Untersuchung gefunden: am häu gsten Rhinoviren und In uenza, danach Boca-, Corona-und Metapneumo-, Parain uenza-Virus und auch Legionellen. Eine saisonale Zuordnung konnte aufgrund der niedrigen Fallzahlen nicht erfolgen [13].…”

Section: Respiratorische Viren Parainfluenzaunclassified

Sommergrippe: Mehr als ein Mythos!

Bogner

2019

MMW - Fortschritte der Medizin

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Sommergrippe: Mehr als ein Mythos! Durchsucht man die deutschsprachige medizinische Literatur nach dem Begriff "Sommer grippe", scheitert man kläglich. Jeder glaubt zu wissen, was damit gemeint ist, doch keiner schreibt darüber. Ist das überhaupt ein seriöses Thema? © Thomas_EyeDesign / Getty Images / iStock (Symbolbild mit Fotomodell) Plötzlich hohes Fieber: Hat sie eine "Sommergrippe"? 39 MMW Fortschritte der Medizin 2019 . 12 / 161 FORTBILDUNG . SCHWERPUNK T 42 MMW Fortschritte der Medizin 2019 . 12 / 161 FORTBILDUNG . SCHWERPUNK T FORTBILDUNG MMW Fortschritte der Medizin 2019 . 12 / 161

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Respiratory infections in elderly people: Viral role in a resident population of elderly care centers in Lisbon, winter 2013–2014

Abstract: In this study an etiologic agent could be found in 60% of the acute respiratory episodes. These data provides information about the circulating viruses in ECC and highlights the importance of searching both viruses and atypical bacteria in severe ARI.

Cited by 17 publications

References 23 publications

Evaluation of Viruses Associated With Acute Respiratory Infections in Long-Term Care Facilities Using a Novel Method: Wisconsin, 2016‒2019

Evaluation of Viruses Associated With Acute Respiratory Infections in Long-Term Care Facilities Using a Novel Method: Wisconsin, 2016‒2019

Respiratory viruses in mechanically ventilated patients: a pilot study

Sommergrippe: Mehr als ein Mythos!

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