2013
DOI: 10.4187/respcare.02412
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Respiratory Care Year in Review 2012: Invasive Mechanical Ventilation, Noninvasive Ventilation, and Cystic Fibrosis

Abstract: SummaryFor the busy clinician, educator, or manager, it is becoming an increasing challenge to filter the literature to what is relevant to one's practice and then update one's practice based on the current evidence. The purpose of this paper is to review the recent literature related to invasive mechanical ventilation, noninvasive ventilation, and cystic fibrosis. These topics were chosen and reviewed in a manner that is most likely to have interest to the readers of RESPIRATORY CARE.

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Cited by 9 publications
(11 citation statements)
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References 63 publications
(51 reference statements)
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“…We previously reviewed invasive ventilation, noninvasive ventilation, and cystic fibrosis. 1 In this paper we publish topics related to asthma and sleep-disordered breathing (SDB).…”
Section: Introductionmentioning
confidence: 99%
“…We previously reviewed invasive ventilation, noninvasive ventilation, and cystic fibrosis. 1 In this paper we publish topics related to asthma and sleep-disordered breathing (SDB).…”
Section: Introductionmentioning
confidence: 99%
“…Based on this finding, we hypothesized that, patients with lower FEV1 0M values had advanced airway destruction and fixed obstruction, resulting in partly restricted admission of inhaled tiotropium. Pulmonary exacerbations are promoted by inflammation and negatively influenced mucociliary clearance, which contribute to a worsening airway obstruction, a decline in lung function, and a profound negative impact on perceived quality of life [ 2 ]. As pulmonary exacerbations have very severe consequences in CF, both in terms of current morbidity as well as implications for long-term morbidity and mortality, the reduction of exacerbation risk is one goal of CF treatment [ 2 , 33 ].…”
Section: Discussionmentioning
confidence: 99%
“…Cystic Fibrosis (CF) is a life-limiting autosomal recessive disorder that affects more than 70,000 individuals worldwide [ 1 , 2 ]. Chronic airway infection, bronchiectasis, hypoxemia and hypercapnia as well as defective mucociliary clearance and bronchial and mucus obstruction are key features of the CF respiratory disease, resulting in a progressive lung function decline.…”
Section: Introductionmentioning
confidence: 99%
“…Subjects were randomized into HFOT and helmet NIV groups. A significantly lower incidence of intubation in the helmet NIV group than in the HFOT group (30% vs. 51%; difference, -21% [95% CI -38% to -3%]; p=0.03) and a higher number of invasive mechanical ventilation-free days at 28 days in the helmet NIV than in the high-flow nasal oxygen group (28 [IQR,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] vs [25][26][27][28]10 .…”
mentioning
confidence: 99%