Resistant psoriasis. Combined methoxsalen-anthralin therapy

Treatment of Psoriasis with Long-Wave Ultraviolet Light

“…Our results are in accordance with observations reported by Willis and Harris [5], and by Stern and K ihiczak [3], In these studies it was reported, among other findings, that neither UV-B nor UV-A in itself had any favour able effect on psoriasis. The negative conclusion with respect to UV-A is amplified by our present result, as we used larger doses of this type of radia tion.…”

Influence of Ultraviolet Light, Various Temperatures, and Zinc Ions on Anthralin (Dithranol)

“…Our results confirm the clinical experiences of highest success rates when anthralin and ultraviolet rays were used together in the treatment of stubborn psoriatic patches. The further addition of a phototoxic substance in this treatment regimen (methoxsalen), will increase the effects of irradiation [11] but will not interfere with the ultraviolet-induced activation of anthralin.…”