Research on transgender and gender diverse (TGD) youth demonstrates the negative outcomes associated with trauma and oppression based on gender identity and expression. Related research illustrates how TGD youth are resilient in the face of oppression through individual (e.g., navigating difficult relationships, seeking mental health support) and community (e.g., access to community resources) factors. However, this research is limited by an understanding of resilience as overcoming challenges rather than exploring the possibly unique ways that TGD youth resist oppression as a form of resilience. This qualitative study utilized in-depth interviews with 19 TGD youth living in two Midwestern states, a region of the U.S. characterized by high levels of hostility and victimization toward TGD young people. Thematic analyses revealed the ways in which TGD youth engage in resistance strategies in the face of oppression. At an intrapersonal level, strategies included resisting oppressive narratives, affirming one’s own gender, maintaining authenticity, and finding hope. At an interpersonal level, strategies were standing up for self and others, educating others, and avoiding hostility. Finally, at a community-level, TGD youth were engaging in activism and organizing and enhancing visibility and representation. Findings are discussed and implications are identified.