Residual Glandular Tissue after Skin-Sparing Mastectomies

Torresan, Renato Zocchio; Santos, César Cabello dos; Brenelli, Henrique Benedito; Okamura, Hélio; Alvarenga, Marcelo

doi:10.1111/j.1075-122x.2005.00029.x

Cited by 13 publications

(6 citation statements)

References 11 publications

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“…Torresan et al looked at the amount of residual breast tissue after SSM by histologically analyzing skin flap specimens, and they found 59.5% of specimens contained residual breast tissue, and 9.5% of skin flaps harbored residual disease [42, 43]. They also concluded that skin flaps >5 mm were associated with the presence of residual disease.…”

Section: The Skin-sparing Mastectomymentioning

confidence: 99%

“…Despite numerous studies previously mentioned, showing no statistical difference between NSSM and SSM in terms of LR, SSM has been shown to be an independent predictor of close or positive margins [42, 43, 45, 46]. Horiguchi et al defined close margin as within 5 mm and did find margin status significant on multivariate analysis [47].…”

Section: The Skin-sparing Mastectomymentioning

confidence: 99%

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Oncologic Safety of Skin-Sparing and Nipple-Sparing Mastectomy: A Discussion and Review of the Literature

Tokin

Weiss

Wang‐Rodriguez

et al. 2012

International Journal of Surgical Oncology

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Breast conservation therapy has been the cornerstone of the surgical treatment of breast cancer for the last 20 years; however, recently, the use of mastectomy has been increasing. Mastectomy is one of the most frequently performed breast operations, and with novel surgical techniques, preservation of the skin envelope and/or the nipple-areolar complex is commonly performed. The goal of this paper is to review the literature on skin-sparing mastectomy and nipple-sparing mastectomy and to evaluate the oncologic safety of these techniques. In addition, this paper will discuss the oncologic importance of margin status and type of mastectomy as it pertains to risk of local recurrence and relative need for adjuvant therapy.

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Section: The Skin-sparing Mastectomymentioning

confidence: 99%

Section: The Skin-sparing Mastectomymentioning

confidence: 99%

Oncologic Safety of Skin-Sparing and Nipple-Sparing Mastectomy: A Discussion and Review of the Literature

Tokin

Weiss

Wang‐Rodriguez

et al. 2012

International Journal of Surgical Oncology

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“…Interestingly, histological studies following conventional mastectomy have confirmed the presence of residual glandular tissue in 5% of all biopsies taken from the operating field [53]. Torresan et al performed histological analysis of skin flaps from patients with IBC and found the prevalence of residual breast tissue to be 59.5% and residual disease to be 9.5%, both significantly associated with skin flaps thicker than 5 mm [54,55]. Ho et al [56] performed histological examinations of the skin and subcutaneous tissue of 30 conventional mastectomy specimens and found that the skin flaps (excluding the NAC) were involved in 23% (7 of 30) of cases.…”

Section: Oncological Considerationsmentioning

confidence: 99%

Oncological and aesthetic considerations of skin-sparing mastectomy

Patani

Mokbel

2007

Breast Cancer Res Treat

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“…4 Benign breast tissue left behind may also give rise to a metachronous second breast carcinoma, as patients with one breast carcinoma are at increased risk of developing another carcinoma. 5 Nonetheless, the superficial specimen margin of SSM has received little attention in the literature. Some pathologists do not even ink the superficial SSM surface, believing that the surgeon has gone as far as he/she can go in this area.…”

Section: Introductionmentioning

confidence: 99%