Repurposing of anti-malarial drugs for the treatment of tuberculosis: realistic strategy or fanciful dead end?
Thomas Hanscheid,
Claire Ruiz del Portal Luyten,
Sabine M. Hermans
et al.
Abstract:Background
Drug repurposing offers a strategic alternative to the development of novel compounds, leveraging the known safety and pharmacokinetic profiles of medications, such as linezolid and levofloxacin for tuberculosis (TB). Anti-malarial drugs, including quinolones and artemisinins, are already applied to other diseases and infections and could be promising for TB treatment.
Methods
This review included studies on the activity of anti-malarial… Show more
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