Repositioning precision of coronary arteries measured on X-ray angiography and its implications for coronary MR angiography

Coppo, Simone; Firsova, Maria; Locca, Didier; Knebel, Jean-François; Heeswijk, Ruud B. van; Stuber, Matthias

doi:10.1002/jmri.24685

Cited by 3 publications

(3 citation statements)

References 33 publications

(49 reference statements)

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“…However, the repositioning of the coronary arteries from beat to beat is not always exact. The repositioning precision has previously been shown to be < 1 mm . In addition, area measurements are performed on cine frames corresponding to periods of minimal cardiac motion, but residual motion may still occur during data acquisition.…”

Section: Discussionmentioning

confidence: 99%

A phantom study to determine the theoretical accuracy and precision of radial MRI to measure cross‐sectional area differences for the application of coronary endothelial function assessment

Yerly

Gubian

Knebel

et al. 2017

Magnetic Resonance in Med

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Section: Discussionmentioning

confidence: 99%

A phantom study to determine the theoretical accuracy and precision of radial MRI to measure cross‐sectional area differences for the application of coronary endothelial function assessment

Yerly

Gubian

Knebel

et al. 2017

Magnetic Resonance in Med

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“…It should also be noted that MR images were collected using segmented techniques acquired over multiple cardiac cycles. The beat-to-beat repositioning precision of the coronary artery has previously been shown to be < 1 mm [34], which implies that the repositioning misalignment could further negatively affect the performance of CMR.…”

Section: Discussionmentioning

confidence: 99%

In vitro optimization and comparison of CT angiography versus radial cardiovascular magnetic resonance for the quantification of cross-sectional areas and coronary endothelial function

Yerly

Becce²,

Heeswijk

et al. 2019

Journal of Cardiovascular Magnetic Resonance

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BackgroundOur objectives were first to determine the optimal coronary computed tomography angiography (CTA) protocol for the quantification and detection of simulated coronary artery cross-sectional area (CSA) differences in vitro, and secondly to quantitatively compare the performance of the optimized CTA protocol with a previously validated radial coronary cardiovascular magnetic resonance (CMR) technique.Methods256-multidetector CTA and radial coronary CMR were used to obtain images of a custom in vitro resolution phantom simulating a range of physiological responses of coronary arteries to stress. CSAs were automatically quantified and compared with known nominal values to determine the accuracy, precision, signal-to-noise ratio (SNR), and circularity of CSA measurements, as well as the limit of detection (LOD) of CSA differences. Various iodine concentrations, radiation dose levels, tube potentials, and iterative image reconstruction algorithms (ASiR-V) were investigated to determine the optimal CTA protocol. The performance of the optimized CTA protocol was then compared with a radial coronary CMR method previously developed for endothelial function assessment under both static and moving conditions.ResultsThe iodine concentration, dose level, tube potential, and reconstruction algorithm all had significant effects (all p < 0.001) on the accuracy, precision, LOD, SNR, and circularity of CSA measurements with CTA. The best precision, LOD, SNR, and circularity with CTA were achieved with 6% iodine, 20 mGy, 100 kVp, and 90% ASiR-V. Compared with the optimized CTA protocol under static conditions, radial coronary CMR was less accurate (− 0.91 ± 0.13 mm2 vs. -0.35 ± 0.04 mm2, p < 0.001), but more precise (0.08 ± 0.02 mm2 vs. 0.21 ± 0.02 mm2, p < 0.001), and enabled the detection of significantly smaller CSA differences (0.16 ± 0.06 mm2 vs. 0.52 ± 0.04 mm2; p < 0.001; corresponding to CSA percentage differences of 2.3 ± 0.8% vs. 7.4 ± 0.6% for a 3-mm baseline diameter). The same results held true under moving conditions as CSA measurements with CMR were less affected by motion.ConclusionsRadial coronary CMR was more precise and outperformed CTA for the specific task of detecting small CSA differences in vitro, and was able to reliably identify CSA changes an order of magnitude smaller than those reported for healthy physiological vasomotor responses of proximal coronary arteries. However, CTA yielded more accurate CSA measurements, which may prove useful in other clinical scenarios, such as coronary artery stenosis assessment.

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“…When performing coronary MRA, a conventional imaging sequence may consist of a navigator for respiratory motion suppression, an ECG-triggered segmented k-space signal readout, and a T 2 -preparation module to enhance contrast between blood and myocardium [ 29 , 30 , 31 , 32 , 33 ]. An adiabatic T 2 -Preparation technique [ 34 ], consisting of a 90° excitation pulse, followed by two hyperbolic secant adiabatic 180° pulses [ 35 ], and a -90° restoration pulse ( Fig 1A ), has previously been shown to be quite effective [ 36 , 37 , 38 , 39 ]. This "conventional" adiabatic T 2 -Prep adds T 2 -weighting, enhancing contrast between the blood and myocardium without the need for a long echo time (TE) ( Fig 1B ).…”

Section: Methodsmentioning

confidence: 99%

A Cylindrical, Inner Volume Selecting 2D-T2-Prep Improves GRAPPA-Accelerated Image Quality in MRA of the Right Coronary Artery

2016

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BackgroundTwo-dimensional (2D) spatially selective radiofrequency (RF) pulses may be used to excite restricted volumes. By incorporating a "pencil beam" 2D pulse into a T2-Prep, one may create a "2D-T2-Prep" that combines T2-weighting with an intrinsic outer volume suppression. This may particularly benefit parallel imaging techniques, where artefacts typically originate from residual foldover signal. By suppressing foldover signal with a 2D-T2-Prep, image quality may therefore improve. We present numerical simulations, phantom and in vivo validations to address this hypothesis.MethodsA 2D-T2-Prep and a conventional T2-Prep were used with GRAPPA-accelerated MRI (R = 1.6). The techniques were first compared in numerical phantoms, where per pixel maps of SNR (SNRmulti), noise, and g-factor were predicted for idealized sequences. Physical phantoms, with compartments doped to mimic blood, myocardium, fat, and coronary vasculature, were scanned with both T2-Preparation techniques to determine the actual SNRmulti and vessel sharpness. For in vivo experiments, the right coronary artery (RCA) was imaged in 10 healthy adults, using accelerations of R = 1,3, and 6, and vessel sharpness was measured for each.ResultsIn both simulations and phantom experiments, the 2D-T2-Prep improved SNR relative to the conventional T2-Prep, by an amount that depended on both the acceleration factor and the degree of outer volume suppression. For in vivo images of the RCA, vessel sharpness improved most at higher acceleration factors, demonstrating that the 2D-T2-Prep especially benefits accelerated coronary MRA.ConclusionSuppressing outer volume signal with a 2D-T2-Prep improves image quality particularly well in GRAPPA-accelerated acquisitions in simulations, phantoms, and volunteers, demonstrating that it should be considered when performing accelerated coronary MRA.

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Repositioning precision of coronary arteries measured on X-ray angiography and its implications for coronary MR angiography

Cited by 3 publications

References 33 publications

A phantom study to determine the theoretical accuracy and precision of radial MRI to measure cross‐sectional area differences for the application of coronary endothelial function assessment

A phantom study to determine the theoretical accuracy and precision of radial MRI to measure cross‐sectional area differences for the application of coronary endothelial function assessment

In vitro optimization and comparison of CT angiography versus radial cardiovascular magnetic resonance for the quantification of cross-sectional areas and coronary endothelial function

A Cylindrical, Inner Volume Selecting 2D-T2-Prep Improves GRAPPA-Accelerated Image Quality in MRA of the Right Coronary Artery

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