volume 4, issue 6, P1559-1567 1985
DOI: 10.1002/j.1460-2075.1985.tb03817.x
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Abstract: Mammalian mitochondrial DNA maintains a novel displacement‐loop region containing the major sites of transcriptional initiation and the origin of heavy strand DNA replication. Because the exact map positions of the 5′ termini of nascent mouse displacement‐loop strands are known, it is possible to examine directly a potential relationship between replication priming and transcription. Analyses of in vivo nucleic acids complementary to the displacement‐loop region reveal two species with identical 5′ ends at ma…

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