PLoS ONE volume 9, issue 5, Pe98276 2014 DOI: 10.1371/journal.pone.0098276 View full text
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Jong-Min Han, Hyeong-Geug Kim, Jin-Seok Lee, Min-Kyung Choi, Young-Ae Kim, Chang-Gue Son

Abstract: Obesity-related disorders, especially metabolic syndrome, contribute to 2.8 million deaths each year worldwide, with significantly increasing morbidity. Eating at regular times and proper food quantity are crucial for maintaining a healthy status. However, many people in developed countries do not follow a regular eating schedule due to a busy lifestyle. Herein, we show that a repeated sense of hunger leads to a high risk of developing visceral obesity and metabolic syndrome in a mouse model (both 3-week and 6…

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