2014
DOI: 10.4172/2161-0681.1000195
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Renal Oncocytoma and Cromophobe Renal Cell Carcinoma: Main Morphological Differences and Proposal of a Simple Histochemical and Immunohistochemical Panel to separate them

Abstract: Introduction: Renal Oncocytoma (RO) and Chromophobe Renal Cell Carcinoma (ChCCR) are within spectrum of "eosinophilic renal neoplasms" that can share morphological features. In some instances, it can be challenging differentiate both entities based only on the HE. For this reason, complementary ancillary techniques are needed.

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Cited by 1 publication
(2 citation statements)
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“…In the study by Ivan G et al (n=38), 18 cases of oncocytoma and 20 cases of chromophobe RCC on histopathological examination were evaluated using special stain and immunohistochemistry. On this basis, he reclassified one case of chromophobe RCC as granular variant of clear cell RCC, two cases of atypical oncocytoma as chromophobe RCC and 2 cases of oncocytoma were reclassified as chromophobe RCC [11] . Chromophobe RCC especially with eosinophilia variant can also be confused with oncocytoma.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In the study by Ivan G et al (n=38), 18 cases of oncocytoma and 20 cases of chromophobe RCC on histopathological examination were evaluated using special stain and immunohistochemistry. On this basis, he reclassified one case of chromophobe RCC as granular variant of clear cell RCC, two cases of atypical oncocytoma as chromophobe RCC and 2 cases of oncocytoma were reclassified as chromophobe RCC [11] . Chromophobe RCC especially with eosinophilia variant can also be confused with oncocytoma.…”
Section: Discussionmentioning
confidence: 99%
“…The ISUP grading system is not applicable for this type of RCC. It has a favorable prognosis and is associated with Birt-Hogg-Dube syndrome [11] . Out of 24 renal neoplasms, 3 cases (33.3%) were Oncocytoma.…”
Section: Discussionmentioning
confidence: 99%