Abstract:Background
Caveolin-1(CAV-1) is a key molecule in cancer metabolism and progression and decrease in highly metastatic breast cancer cells. Moreover, glutamine is a crucial amino acid in the tumor microenvironment, and cancer cells are addicted to it. The effect of glutamine metabolism on caveoline-1 was not completely clarified. However, metformin has been demonstrated in separate studies to impair glutamine metabolism, and also affect caveoline-1 expression. Hence, the focus of this study is to evaluate the … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.