Knowledge systems-networks of linked actors, organizations, and objects that perform a number of knowledge-related functions that link knowledge and know how with action-have played a key role in fostering agricultural development over the last 50 years. We examine the evolution of the knowledge system of the Yaqui Valley, Mexico, a region often described as the home of the green revolution for wheat, tracing changes in the functions of critical knowledge system participants, information flows, and research priorities. Most of the knowledge system's key players have been in place for many decades, although their roles have changed in response to exogenous and endogenous shocks and trends (e.g., drought, policy shifts, and price trends). The system has been agile and able to respond to challenges, in part because of the diversity of players (evolving roles of actors spanning research-decision maker boundaries) and also because of the strong and consistent role of innovative farmers. Although the agricultural research agenda in the Valley is primarily controlled from within the agricultural sector, outside voices have become an important influence in broadening development-and production-oriented perspectives to sustainability perspectives.environmental sustainability | technology adoption | fertilizer and water management O ver the last 50 years, agricultural communities in developing countries have experienced dramatic changes in their requirements for and access to information, knowledge, and know how related to cropping systems and commodity markets (1). As part of a post-World War II effort to enhance agricultural production, research systems focused on development and deployment of improved genetic materials and management practices for key food staple crops (2, 3). Over time, with the changing landscape of agricultural production (4, 5), transformations in global food demand and marketing systems (6), and increasing foci on sustainability objectives, including environmental concerns, these systems have been required to evolve to continue providing relevant support.In this paper, we explore the evolution of knowledge systems for agricultural development that has occurred in the home of the green revolution for wheat. Knowledge systems are networks of linked actors, organizations, and objects that perform a number of knowledge-related functions that link knowledge and know how with action (including research, innovation, development, demonstration, deployment, and adoption).* They include the institutions, human capital, financial resources, and incentives that give such systems the capacity to function. Although knowledge systems are not the result of master design, they can be understood and manipulated in ways that improve their performance. Previous research has highlighted communication and translation among players within knowledge systems as key functions for managing the boundaries between scientific knowledge and decision making (7-9). To date, little attention has been paid to how these functions ch...