Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings

Marshall, Michelle; Jónsson, Helgi; Helgadottir, G.P.; Windt, Daniëlle van der; Myers, Helen; Dziedzic, Krysia

doi:10.1002/acr.22225

Cited by 10 publications

(18 citation statements)

References 25 publications

(44 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…affected by osteoarthritis (OA) and healthy joints 232 . After further methodological refinements, this technique could distinguish between patients with hand OA and patients with psoriatic arthritis or healthy individuals 233 . Incorporating PAI with DOT improves the image resolution enabling better differentiation of bone from soft tissue 234 .…”

Section: [H1] Conclusionmentioning

confidence: 99%

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management

et al. 2018

Self Cite

View full text Add to dashboard Cite

Osteoarthritis (OA) is a highly prevalent condition and the hand is the most commonly affected site. Patients with hand OA frequently report symptoms of pain, functional limitations, and frustration in undertaking everyday activities. The condition presents clinically with changes to the bone, ligaments, cartilage and synovial tissue, which can be observed using radiography, ultrasonography or MRI. Hand OA is a heterogeneous disorder and is considered to be multifactorial in aetiology. This review provides an overview of the epidemiology, presentation and burden of hand OA, including an update on hand OA imaging (including the development of novel techniques), disease mechanisms and management. In particular, areas for which new evidence has substantially changed the way we understand, consider and treat hand OA are highlighted. For example, genetic studies, clinical trials and careful prospective imaging studies from the past 5 years are beginning to provide insights into the pathogenesis of hand OA that might uncover new therapeutic targets in disease.

show abstract

Section: [H1] Conclusionmentioning

confidence: 99%

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…Two a priori hypotheses were set regarding these correlations at the joint and joint group level: 1) Change in photographic hand OA scores for each joint was expected to correlate more closely with the change in the number of clinical features than with the change in radiographic OA grade. 2) Correlations would be the same or slightly lower than was achieved at baseline for cross-sectional construct validity in each hand joint and joint group [11].…”

Section: Discussionmentioning

confidence: 99%

“…Reliability of using the photographic scoring system has previously been established [11], thus reliability was undertaken at 7-years to ensure that this hadn't markedly changed. The inter-rater reliability of the scoring of photographic hand Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Correlations in each hand joint and joint group were, for * Relaxed ACR criteria is when there is pain on some, most or all days rather than most days or all days in the ACR criteria. s.d., standard deviation; BMI, Body mass Index; ACR, American College of Rheumatology; KL, Kellgren and Lawrence grading system the most part, lower than was achieved for construct validity at baseline [11].…”

Section: Joint-level Associations With Photographic Hand Oa Progressimentioning

confidence: 95%

“…In 2012, the Age, Gene/Environment Susceptibility -Reykjavik (AGES-Reykjavik) photographic atlas was developed as a formal method for scoring hand photographs for OA [9]. It has been shown to be reliable and associated cross-sectionally with radiographic and clinical OA [10,11] and shows age-related prevalence trends that are comparable to those seen for clinical and radiographic OA [12]. However, it is not known whether this method is valid in comparison to the progression of radiographic OA and the increased presence of clinical features determined from a physical examination.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain

Marshall

Jónsson

Helgadóttir

et al. 2019

Preprint

Self Cite

View full text Add to dashboard Cite

Background: To determine the longitudinal construct validity of assessing hand OA progression on digital photographs over 7 years compared with progression determined from radiographs, clinical features and change in symptoms. Methods: Participants were community-dwelling older adults (≥50 years) in North Staffordshire, UK. Standardized digital hand photographs were taken at baseline and 7 years, and hand joints graded for OA severity using an established photographic atlas. Radiographic hand OA was assessed using the Kellgren and Lawrence grading system. Hand examination determined the presence of nodes, bony enlargement and deformity. Symptoms were reported in self-complete questionnaires. Radiographic and clinical progression and change in symptoms were compared to photographic progression. Differences were examined using analysis of covariance and Chi-Square tests. Results: Of 253 individuals (61% women, mean age 63 years) the proportion with photographic progression at the joint and joint group-level was higher in individuals with radiographic or clinical progression compared to those without, although differences were not statistically significant. At the person-level, those with moderate photographic progression over 7 years had significantly higher summed radiographic and clinical scores (adjusted for baseline scores) compared to those with no or mild photographic progression. Similar findings were observed for change in symptoms, although differences were small and not statistically significant. Conclusion: Assessing hand OA on photographs shows modest longitudinal construct validity over 7 years compared with change in radiographic and clinical hand OA at the person-level. Using photographs to assess overall long-term change in a person with hand OA may be a reasonable alternative when hand examinations and radiographs are not feasible.

show abstract

Hand and knee osteoarthritis are associated with reduced diameters in retinal vessels: the AGES-Reykjavik study

et al. 2019

Self Cite

View full text Add to dashboard Cite

To investigate the association between osteoarthritis (OA) and microvascular pathology, we examined the relationship between retinal microvascular caliber and osteoarthritis of the hand and knee in an elderly population. The AGES-Reykjavik is a population-based, multidisciplinary longitudinal cohort study of aging. Retinal vessel caliber, hand osteoarthritis and total knee joint replacements due to OA were examined in 4757 individuals (mean age 76 ± 5 years; 57% female). Incident knee joint replacements during 5-year follow-up (n = 2961, mean age 75 ± 5 years; 58% female) were also assessed. Logistic regression analysis, adjusting for age, sex, and body mass index, showed an association between narrow arteriolar caliber and hand OA, as well as knee replacement. After adjustment for other covariates, including statin therapy, this association was significant for both hand OA in men and women [OR 1.10(1.03-1.17), p < 0.01] (per unit standard deviation decrease in CRAE) and TKR prevalence [OR 1.15 (1.01-1.32), p = 0.04], especially for men [OR 1.22 (1.00-1.51) p = 0.04] and also for incident TKRs in men [OR 1.50 (1.07-2.10), p = 0.04]. Narrow venular caliber was associated with hand OA in women [OR 1.10 (1.01-1.21), p = 0.03]. Retinal arterial narrowing in hand and knee OA is present in males as well as females.Helgi Jonsson, helgi@hi.is. Author contributions All authors have: (1) made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data; (2) been involved in drafting the manuscript or revising it critically for important intellectual content; (3) given final approval of the version to be published; and (4) agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Conflict of interestThe authors have no proprietary or commercial interest in any materials discussed in this article.Ethical standards All procedures performed were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments. Both studies were approved by the Icelandic National Bioethics Committee, (VSN: 00-063, and VSN 09_098_S1) and the Data Protection Authority. Ethical approvalBoth studies were approved by the Icelandic National Bioethics Committee, (VSN: 00-063, and VSN 09_098_S1) and the Data Protection Authority.Informed consent All participants signed an informed consent declaration. Consent to publishThe study is approved by the AGES-Reykjavik steering committee.Data availability All data are from the AGES-Reykjavik study and can be obtained upon application.

show abstract

Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings

Cited by 10 publications

References 25 publications

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management

Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain

Hand and knee osteoarthritis are associated with reduced diameters in retinal vessels: the AGES-Reykjavik study

Contact Info

Product

Resources

About