Relative risks of adolescent and young adult alcohol use: The role of drinking fathers, mothers, siblings, and friends

Scholte, Ron H. J.; Poelen, Evelien A. P.; Willemsen, Gonneke; Boomsma, Dorret I.; Engels, Rutger C. M. E.

doi:10.1016/j.addbeh.2007.04.015

Cited by 106 publications

(85 citation statements)

References 55 publications

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“…Studies on this topic showed that early matured girls are likely to affiliate with older and deviant peers (Caspi et al, 1993). Previous analyses of our data indeed showed a trend being indicative that friends' drinking was a greater risk factor for drinking in females compared to males (Scholte et al, 2008).…”

Section: Discussionsupporting

confidence: 69%

The Relative Contribution of Genes and Environment to Alcohol Use in Early Adolescents: Are Similar Factors Related to Initiation of Alcohol Use and Frequency of Drinking?

Poelen

Derks

Engels

et al. 2008

Alcoholism Clin & Exp Res

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Background: The present study assessed the relative contribution of genes and environment to individual differences in initiation of alcohol use and frequency of drinking among early adolescents and examined the extent to which the same genetic and environmental factors influence both individual differences in initiation of alcohol use and frequency of drinking.Methods: Questionnaire data collected by the Netherlands Twin Register were available for 694 twin pairs aged of 12 to 15 years. Bivariate genetic model fitting analyses were conducted in mx. We modeled the variance of initiation of alcohol use and frequency of drinking as a function of three influences: genetic effects, common environmental effects, and unique environmental effects. Analyses were performed conditional on sex.Results: Findings indicated that genetic factors were most important for variation in early initiation of alcohol use (83% explained variance in males and 70% in females). There was a small contribution of common environment (2% in males, 19% in females). In contrast, common environmental factors explained most of the variation in frequency of drinking (82% in males and females). In males the association between initiation and frequency was explained by common environmental factors influencing both phenotypes. In females, there was a large contribution of common environmental factors that influenced frequency of drinking only. There was no evidence that different genetic or common environmental factors operated in males and females.Conclusion: Different factors were involved in individual differences in early initiation of alcohol use and frequency of drinking once adolescents have started to use alcohol.

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Section: Discussionsupporting

confidence: 69%

The Relative Contribution of Genes and Environment to Alcohol Use in Early Adolescents: Are Similar Factors Related to Initiation of Alcohol Use and Frequency of Drinking?

Poelen

Derks

Engels

et al. 2008

Alcoholism Clin & Exp Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…It might be that adolescents with permissive parents, who encounter heavy drinking friends will start earlier, or consume more alcohol than those without these adverse environmental factors. 67 Therefore, large prospective population studies are required to examine the broad spectrum of etiological factors responsible for the development of alcohol abuse. 68 It is not clear how the DRD2 gene exerts its effect on alcohol use in the group of adolescents with permissive parents.…”

Section: -40mentioning

confidence: 99%

Interaction between dopamine D2 receptor genotype and parental rule-setting in adolescent alcohol use: evidence for a gene-parenting interaction

et al. 2009

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Association studies investigating the link between the dopamine D2 receptor gene (DRD2) and alcohol (mis)use have shown inconsistent results. This may be due to lack of attention for environmental factors. High levels of parental rule-setting are associated with lower levels of adolescent alcohol use and delay of initiation of drinking. We tested whether DRD2 TaqI A (rs1800497) genotype interacts with alcohol-specific parenting practices in predicting the uptake of regular adolescent alcohol use. Non-regular drinkers were selected from a Dutch, nationwide sample of 428 adolescents (mean age 13.4 years at baseline) and participated in a prospective, community-based study with three annual waves. Parental rule-setting was directly and inversely related to adolescent alcohol use over time. For DRD2 genotype no significant main effect was found. DRD2 genotype interacted with parental rule-setting on adolescent alcohol use over time: adolescents, with parents highly permissive toward alcohol consumption and carrying a genotype with the DRD2 A1 (rs1800497T) allele, used significantly more alcohol over time than adolescents without these characteristics. The DRD2 genotype may pose an increased risk for alcohol use and abuse, depending on the presence of environmental risk factors, such as alcohol-specific parenting.

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“…A transmissão transgeracional dessa síndrome é um tema de estudo frequente na literatura nacional e internacional. Pais que fazem uso de alguma droga servem de modelo tanto para meninos quanto para meninas na experimentação e no início do contato com álcool e outras drogas [15][16][17][18][19] .…”

Section: Transmissão Transgeracional Do Uso De áLcool E Drogasunclassified

Aspectos familiares de meninas adolescentes dependentes de álcool e drogas

Guimarães¹,

Hochgraf²,

Brasiliano³

et al. 2009

Rev. psiquiatr. clín.

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Relative risks of adolescent and young adult alcohol use: The role of drinking fathers, mothers, siblings, and friends

Cited by 106 publications

References 55 publications

The Relative Contribution of Genes and Environment to Alcohol Use in Early Adolescents: Are Similar Factors Related to Initiation of Alcohol Use and Frequency of Drinking?

The Relative Contribution of Genes and Environment to Alcohol Use in Early Adolescents: Are Similar Factors Related to Initiation of Alcohol Use and Frequency of Drinking?

Interaction between dopamine D2 receptor genotype and parental rule-setting in adolescent alcohol use: evidence for a gene-parenting interaction

Aspectos familiares de meninas adolescentes dependentes de álcool e drogas

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