2013
DOI: 10.1002/hep.26535
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Abstract: RAI is frequent in noncritically ill patients with acute decompensation of cirrhosis. As compared with those with normal adrenal function, patients with RAI have greater impairment of circulatory and renal function, higher probability of severe sepsis and type-1 HRS, and higher short-term mortality.

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Cited by 122 publications
(169 citation statements)
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References 45 publications
(75 reference statements)
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“…A very recent study confirmed the high prevalence and the relevance of AD in noncritically ill cirrhotic patients, as patients with AD are at higher risk of circulatory and renal dysfunction, sepsis, and death [12].…”
Section: Introductionmentioning
confidence: 85%
See 1 more Smart Citation
“…A very recent study confirmed the high prevalence and the relevance of AD in noncritically ill cirrhotic patients, as patients with AD are at higher risk of circulatory and renal dysfunction, sepsis, and death [12].…”
Section: Introductionmentioning
confidence: 85%
“…In patients with advanced cirrhosis without sepsis or other acute distress, data are limited [12][13][14][15][16]. A very recent study confirmed the high prevalence and the relevance of AD in noncritically ill cirrhotic patients, as patients with AD are at higher risk of circulatory and renal dysfunction, sepsis, and death [12].…”
Section: Introductionmentioning
confidence: 92%
“…49 In a recent study, low cortisol level was associated with impairments of circulatory and renal function, higher likelihood of development of severe sepsis and type I HRS, as well as higher short-term mortality. 50 Although the occurrence of relative adrenal insufficiency appears to be exaggerated in patients with cirrhosis and septic shock, whether replacement doses of hydrocortisone affect outcome remains unknown.…”
Section: Hydrocortisonementioning
confidence: 99%
“…Within these studies, a range of prevalence of AI has been demonstrated, from 6.3% to 58% depending on the adrenal function assay used (Table 21.1). More recently, AI has been associated with the incidence of complications and death in a large cohort of patients with cirrhosis [26].…”
Section: Prevalence Of Adrenal Insufficiency In Stable Cirrhosismentioning
confidence: 99%