Relationships between number, size and shape of red blood cells in amphibians

Partial characterization of a novel amphibian hemoglobin as a model for graduate student investigation on peptide chemistry, mass spectrometry, and atomic force microscopy

“…The students immediately suspected that the glass slide contained a blood smear due to the red color; however, they were surprised by the fact that the cells had an elongated instead of discoid form as they imagined from the largely known mammalian red blood cell structure. In fact, the results confirmed and reinforced the well‐established fact that amphibians have elliptical and larger red blood cells [20] when compared to the mammalian cells (Figs. 1 a and 1 b ).…”

Partial characterization of a novel amphibian hemoglobin as a model for graduate student investigation on peptide chemistry, mass spectrometry, and atomic force microscopy

“…The students immediately suspected that the glass slide contained a blood smear due to the red color; however, they were surprised by the fact that the cells had an elongated instead of discoid form as they imagined from the largely known mammalian red blood cell structure. In fact, the results confirmed and reinforced the well‐established fact that amphibians have elliptical and larger red blood cells [20] when compared to the mammalian cells (Figs. 1 a and 1 b ).…”

The Nuclear-to-Cytoplasmic Ratio: Coupling DNA Content to Cell Size, Cell Cycle, and Biosynthetic Capacity

“…Genome size varies from 160 kilobase pairs (kbp) in the bacteria Candidatus Carsonella ruddii (117) to 150 × 10 6 kbp in the understory plant Paris japonica (129). Genome size is a major correlate of both nuclear and cell size in a variety of taxonomic groups, including fungi, animals, and plants (65,111,113,114,126). For example, among salamanders of the genus Batrachoseps, genome size varies by billions of base pairs, and as genome size increases, there are corresponding changes in nuclear volume and erythrocyte area (114).…”

Do blood parasites increase immature erythrocytes and mitosis in amphibians?

“…Amphibian RBCs' lifespans range from 200 to 1 400 days (Altland & Brace, 1962); their RBCs (mainly in salamanders) are the largest among vertebrates, e.g., Amphiuma tridactylum RBCs sizes are approximately 70 μm length and 40 μm width. In contrast, frogs and toads, have the smallest RBCs of amphibians, 22 μm length and 15 μm width on average (Mitsuru, 1981;Claver & Quaglia, 2009;Arikan & Cicek, 2014).…”

Partial characterization of a novel amphibian hemoglobin as a model for graduate student investigation on peptide chemistry, mass spectrometry, and atomic force microscopy

“…The students immediately suspected that the glass slide contained a blood smear due to the red color; however, they were surprised by the fact that the cells had an elongated instead of discoid form as they imagined from the largely known mammalian red blood cell structure. In fact, the results confirmed and reinforced the well‐established fact that amphibians have elliptical and larger red blood cells [20] when compared to the mammalian cells (Figs. 1 a and 1 b ).…”

The Nuclear-to-Cytoplasmic Ratio: Coupling DNA Content to Cell Size, Cell Cycle, and Biosynthetic Capacity

“…Genome size varies from 160 kilobase pairs (kbp) in the bacteria Candidatus Carsonella ruddii (117) to 150 × 10 6 kbp in the understory plant Paris japonica (129). Genome size is a major correlate of both nuclear and cell size in a variety of taxonomic groups, including fungi, animals, and plants (65,111,113,114,126). For example, among salamanders of the genus Batrachoseps, genome size varies by billions of base pairs, and as genome size increases, there are corresponding changes in nuclear volume and erythrocyte area (114).…”

Do blood parasites increase immature erythrocytes and mitosis in amphibians?

“…Amphibian RBCs' lifespans range from 200 to 1 400 days (Altland & Brace, 1962); their RBCs (mainly in salamanders) are the largest among vertebrates, e.g., Amphiuma tridactylum RBCs sizes are approximately 70 μm length and 40 μm width. In contrast, frogs and toads, have the smallest RBCs of amphibians, 22 μm length and 15 μm width on average (Mitsuru, 1981;Claver & Quaglia, 2009;Arikan & Cicek, 2014).…”

Partial characterization of a novel amphibian hemoglobin as a model for graduate student investigation on peptide chemistry, mass spectrometry, and atomic force microscopy

“…The students immediately suspected that the glass slide contained a blood smear due to the red color; however, they were surprised by the fact that the cells had an elongated instead of discoid form as they imagined from the largely known mammalian red blood cell structure. In fact, the results confirmed and reinforced the well‐established fact that amphibians have elliptical and larger red blood cells [20] when compared to the mammalian cells (Figs. 1 a and 1 b ).…”

The Nuclear-to-Cytoplasmic Ratio: Coupling DNA Content to Cell Size, Cell Cycle, and Biosynthetic Capacity

“…Genome size varies from 160 kilobase pairs (kbp) in the bacteria Candidatus Carsonella ruddii (117) to 150 × 10 6 kbp in the understory plant Paris japonica (129). Genome size is a major correlate of both nuclear and cell size in a variety of taxonomic groups, including fungi, animals, and plants (65,111,113,114,126). For example, among salamanders of the genus Batrachoseps, genome size varies by billions of base pairs, and as genome size increases, there are corresponding changes in nuclear volume and erythrocyte area (114).…”

Do blood parasites increase immature erythrocytes and mitosis in amphibians?

“…Amphibian RBCs' lifespans range from 200 to 1 400 days (Altland & Brace, 1962); their RBCs (mainly in salamanders) are the largest among vertebrates, e.g., Amphiuma tridactylum RBCs sizes are approximately 70 μm length and 40 μm width. In contrast, frogs and toads, have the smallest RBCs of amphibians, 22 μm length and 15 μm width on average (Mitsuru, 1981;Claver & Quaglia, 2009;Arikan & Cicek, 2014).…”