2011
DOI: 10.1186/1476-511x-10-61
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Abstract: BackgroundDespite oxidized low density lipoprotein (ox-LDL) plays important roles in the pro-inflammatory and atherosclerotic processes, the relationships with metabolic and oxidative stress biomarkers have been only scarcely investigated in young adult people. Thus, the aim of this study was to assess plasma ox-LDL concentrations and the potential association with oxidative stress markers as well as with anthropometric and metabolic features in healthy young adults.MethodsThis study enrolled 160 healthy subje… Show more

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Cited by 23 publications
(23 citation statements)
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“…In agreement with this hypothesis, we recently also published data that relates SUA level with the ones of other markers of systemic oxidative stress related to cardiovascular disease, the serum level of oxidized low density lipoproteins (LDL) and dienes, in a relatively large sample of overall healthy adult-elderly men and women [3]. Similar results have been previously observed by Barbosa et al [4] in a smaller sample of younger subjects and by Ruíz-Hernández-et al [5]., who limited their study on overweight women. We also observed that SUA was associated with the dienes level, but not with the LDL lag phase and propagation phase length.…”
supporting
confidence: 88%
“…In agreement with this hypothesis, we recently also published data that relates SUA level with the ones of other markers of systemic oxidative stress related to cardiovascular disease, the serum level of oxidized low density lipoproteins (LDL) and dienes, in a relatively large sample of overall healthy adult-elderly men and women [3]. Similar results have been previously observed by Barbosa et al [4] in a smaller sample of younger subjects and by Ruíz-Hernández-et al [5]., who limited their study on overweight women. We also observed that SUA was associated with the dienes level, but not with the LDL lag phase and propagation phase length.…”
supporting
confidence: 88%
“…[17] Ox-LDL (oxidized low density lipoprotein, a confirmed marker for oxidative stress) concentrations were positively associated with specific lipid biomarkers (total cholesterol, LDL-c and total cholesterol-to-HDL-c ratio), GPx activity and uric acid concentration. [18] Obese individuals, according to another study demonstrated a fundamentally altered epidermal barrier. [19] The events of acne vulgaris appear to be affected by obesity, hormonal and immune-mediated mechanisms that potentiate the inflammatory response.…”
Section: Discussionmentioning
confidence: 93%
“…Insulin resistance is a major precursor of CVD and type 2 diabetes (30) and among children, the reliability of HOMA-IR for its measurement is well established (24) . Moreover, the ratio TC:HDL-C is a positive predictor of oxidized LDL concentrations, playing an important role in the atherosclerotic process (28) . Comparison of studies that explore the feasibility of overweight to identify fat children is challenging, as different BMI and adiposity cut-offs are proposed (17,43,44) .…”
Section: Discussionmentioning
confidence: 99%
“…HOMA-IR higher than 3·2 was considered abnormal (24) . Based on adult observations, TC:HDL-C greater than 4·5 was considered adverse (27,28) . From 6 to 9 years old and from 10 to 12 years old, hypertension was considered as systolic and diastolic BP levels ≥122/78 mmHg and ≥126/82 mmHg, respectively (29) .…”
Section: Definition Of Adverse Cardiometabolic Profilementioning
confidence: 99%