Relationship of lumbosacral nevocytic nevi to sun exposure in dysplastic nevus syndrome

²

,

Bart

³

et al. 1990

0

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…Those pigmented lesions that had the clinical features of ephelides, solar lentigines, seborrheic keratoses, verrucae, acrochordons, etc, were excluded. Previous studies from our group showed that there is consistency among observers in differentiating NN from other pigmented cutaneous neoplasms by this method 6 …”

Section: Methodsmentioning

confidence: 81%

Does a History of Melanoma Correlate with the Clinical Presentation of Dysplastic Nevi?

GOLDMAN

¹

,

²

,

Bart

³

et al. 1990

0

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…Sun sensitivity, as well as the absolute number of nevocytic nevi, increases an individual's risk for developing MM 14–23 . DN patients may have hundreds of nevocytic nevi 24 and demonstrate an increased number of both “common acquired” and atypical nevocytic nevi on sun‐exposed skin 5,6 . This would suggest that the melanocytic system in such individuals has been activated by sunlight and that a proportion of these cells may become neoplastic, resulting in the production of DN.…”

Section: Discussionmentioning

confidence: 99%

“…Subsequently, DN have also been shown to occur in the nonfamilial (sporadic) setting. In patients with DN, Kopf et al 5,6 have presented data to suggest that DN are larger and more numerous on relatively sun‐exposed (versus sun‐protected) sites. Thus, the occurrence of many DN seems to be related to sunlight exposure.…”

Section: Introductionmentioning

confidence: 99%

Skin Types in Dysplastic Nevus Syndrome

¹

,

GOLDMAN

²

,

Rivers

³

et al. 1988

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…This may be reflected in the high propensity for the development of MM in patients who have large congenital nevocytic nevi (Quaba and Wallace, 1986). Sun-exposed areas of the skin have a higher concentration of nevocytic nevi per unit area than sunprotected areas (Kopf et al, 1978(Kopf et al, , 1985(Kopf et al, , 1986. Therefore, the number of moles may express the susceptibility of the melanocytes to undergo benign (nevus cell) proliferation in response to sunlight exposure.…”

Section: Nevocytic Nevimentioning

confidence: 99%

Risk Factors for the Development of Malignant Melanoma—I: Review of Case‐Control Studies

EVANS

¹

,

²

,

Lew

³

et al. 1988