Relationship of Body Mass Index With Total Mortality, Cardiovascular Mortality and Myocardial Infarction After Coronary Revascularization: Evidence From a Meta-Analysis

Sharma, Abhishek; Vallakati, Ajay; Lavie, Carl J.; Arbab‐Zadeh, Armin; López-Jiménez, Francisco; Mukherjee, Debabrata; Lichstein, Edgar

doi:10.1016/s0735-1097(14)61355-3

Cited by 17 publications

(42 citation statements)

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“…It is also considered an easy and rapid indicator to obtain, especially in the context of primary health care. Recent analyzes have shown that this ratio is a potent predictor of the development of coronary heart disease and is directly correlated with plasma B-type LDLcholesterol levels [5][6][7][8] . As such, the objective of the present study was to evaluate the association between the TG/HDL-c ratio and cardiovascular risk factors among elderly persons receiving care under the Estratégia Saúde da Família (Family Health Strategy) (ESF) in the municipal district of Viçosa, Minas Gerais, Brazil.…”

Section: Introductionmentioning

confidence: 99%

Association between triglycerides and HDL-cholesterol ratio and cardiovascular risk factors among elderly persons receiving care under the family health strategy of Viçosa, Minas Gerais

Martins

Souza

Martinho

et al. 2017

Rev. bras. geriatr. gerontol.

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Objective: To evaluate the association between triglycerides and HDL-cholesterol (TG/ HDL-c) ratio and cardiovascular risk factors among the elderly. Method: A cross-sectional epidemiological study with a random sample of elderly persons (n=349) of both genders, who received care under the Family Health Strategy in the municipality of Viçosa, in the state of Minas Gerais, was performed. Cardiovascular risk was calculated by the relationship between the TG and the HDL-c levels, with values greater than 3.5 considered a risk. Social and economic variables, lifestyle, noncommunicable chronic diseases, serum glucose levels, waist circumference (WC) and body mass index were evaluated. Multiple linear regression was used to evaluate the association between the TG/HDL-c ratio and other variables. Variables associated with the dependent variable with a level of significance lower than 0.20 in univariate regression analysis were included in the final model (stepwise-forward), applying a significance level of p<0.05. Results: The highest TG/HDL-c ratio values were associated with the presence of hypertension, having been or currently be a smoker, having elevated serum glucose and an increased waist circumference. Conclusion: The findings reflect the importance of studies on cardiovascular risk in the elderly, as health professionals should be familiar with the parameters that classify at risk individuals. The TG/HDL-c ratio is a reliable classification method that is easy to apply and correlates closely with adverse health effects.

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Section: Introductionmentioning

confidence: 99%

Association between triglycerides and HDL-cholesterol ratio and cardiovascular risk factors among elderly persons receiving care under the family health strategy of Viçosa, Minas Gerais

Martins

Souza

Martinho

et al. 2017

Rev. bras. geriatr. gerontol.

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“…Notwithstanding many devastating consequences of obesity in health and disease, emerging data suggest that there is existence of an obesity paradox, in that higher BMI counterintuitively protects against adverse outcomes in many acute and chronic disease states. 3, 4 This seemingly counterintuitive obesity survival advantage has been observed despite prior data showing that obesity is a risk factor in the development of many acute and chronic disease states conferring high mortality such as coronary artery disease, 1, 5 heart failure, 6 chronic kidney disease, 7 end-stage renal disease, 8, 9 and malignancy, 10 as well as advanced age, 11 and despite the consistent association of obesity with poor health-related quality of life. 12 These provocative observations of an inverse association between obesity and greater survival are also one of several cardiovascular (CV) risk factors that demonstrate a “reverse epidemiology” pattern among certain chronic disease populations such as dialysis or heart failure patients, and also include the lipid paradox and hypertension paradox, i.e., survival advantages of higher lipid level concentrations and higher blood pressure values.…”

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confidence: 98%

“…1, 2 Whereas a BMI >25 kg/m 2 and up to 30 kg/m 2 are referred to as being overweight, a BMI <25 kg/m 2 is generally considered ideal, although there is less consensus as to what the lower threshold of the normal BMI range should be. Notwithstanding many devastating consequences of obesity in health and disease, emerging data suggest that there is existence of an obesity paradox, in that higher BMI counterintuitively protects against adverse outcomes in many acute and chronic disease states.…”

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confidence: 99%

To Legitimize the Contentious Obesity Paradox

Kalantar-Zadeh

Rhee

Amin

2014

Mayo Clinic Proceedings

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“…Moreover, underweight individuals with one of several prevalent diseases also show marked increases in mortality, compared with their normal-weight counterparts (22)(23)(24) . Thus, the inclusion of participants with underlying disease or poor health may limit analyses (8,10,11,25,26) .…”

Section: Discussionmentioning

confidence: 99%

Underweight and mortality

Lee

Kim

et al. 2015

Public Health Nutr.

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Objective: According to most prospective studies, being underweight (BMI <18·5 kg/m 2 ) is associated with significantly higher mortality than being of normal weight, especially among smokers. We aimed to explore in a generally lean population whether being underweight is significantly associated with increased all-cause mortality. Design: Prospective cohort study. Setting: Korea Medical Insurance Corporation study with 14 years of follow-up. Subjects: After excluding deaths within the first 5 years of follow-up (1993-1997) to minimize reverse causation and excluding participants without information about smoking and health status, 94 133 men and 48 496 women aged 35-59 years in 1990 were included. Results: We documented 5411 (5·7 %) deaths in men and 762 (1·6 %) in women. Among never smokers, hazard ratios (HR) for underweight individuals were not significantly higher than those for normal-weight individuals (BMI = 18·5-22·9 kg/m 2 ): HR = 0·87 (95 % CI 0·41, 1·84, P = 0·72) for underweight men and HR = 1·12 (95 % CI 0·76, 1·65, P = 0·58) for underweight women. Among ex-smokers, HR = 0·86 (95 % CI 0·38, 1·93, P = 0·72) for underweight men and HR = 3·77 (95 % CI 0·42, 32·29, P = 0·24) for underweight women. Among current smokers, HR = 1·60 (95 % CI 1·28, 2·01, P < 0·001) for underweight men and HR = 2·07 (95 % CI 0·43, 9·94, P = 0·36) for underweight women. Conclusions: The present study does not support that being underweight per se is associated with increased all-cause mortality in Korean men and women.

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Relationship of Body Mass Index With Total Mortality, Cardiovascular Mortality and Myocardial Infarction After Coronary Revascularization: Evidence From a Meta-Analysis

Cited by 17 publications

References 0 publications

Association between triglycerides and HDL-cholesterol ratio and cardiovascular risk factors among elderly persons receiving care under the family health strategy of Viçosa, Minas Gerais

Association between triglycerides and HDL-cholesterol ratio and cardiovascular risk factors among elderly persons receiving care under the family health strategy of Viçosa, Minas Gerais

To Legitimize the Contentious Obesity Paradox

Underweight and mortality

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