Relationship Between the B-Mitten EEG Pattern and Tardive Dyskinesia

A Long Term Prospective Study of Electroencephalographic and Neuropsychological Correlates of Tardive Dyskinesia: Initial Findings at Five Year Follow-Up

“…Our own report " based on a sample of 850 cases of Mittens indicates that less than 5% of the Mitten cases can be expected after age 50. Furthermore we have reported previously 25,26,44 that the relationship of the Mitten dysrhythmia to clinical TO does not hold at all for older subjects and that the association is only seen among younger patients.…”

Tardive Dyskinesia: Clinical, Biological, and Pharmacological Perspectives

“…In addition to neuroleptic therapy, various other factors may be involved in the development of tardive dyskinesia including the age and sex of the patient, genetic predisposition, preexisting organic brain disease, duration and total dose of neuroleptics or other medications, and previous ECT. Wegner et al (1979) found a high prevalence of the rare B-mitten EEG dysrhythmia which they suggest may indicate a preexisting structural or functional vulnerability to neuroleptic-induced dysregulation. The use of drug holidays has been recommended as a method of reducing the risk and in-creasing early recognition of tardive dyskinesia.…”

Electroencephalogram in Tardive Dyskinesia

“…Lithium induced EEG changes will disappear a week after lithium is dtscontlnued" The paroxysmal abnormalities observed in the present study were most likely drug induced. Wegner et al 6 and Struve and Willner 20 have suggested that a specific EEG pattern, B mitten, is a risk factor for tardive dyskinesia. The B mitten pattern consists of sharp transients followed by a higher voltage slow-wave which is detected during deep sleep recordings.…”