Relationship Between Respiratory Muscle Strength and Conventional Sarcopenic Indices in Young Adults: A Preliminary Study

Abstract

ObjectiveTo investigate the relationships between respiratory muscle strength and conventional sarcopenic indices such as skeletal muscle mass and limb muscle strength.MethodsEighty-nine young adult volunteers who had no history of medical or musculoskeletal disease were enrolled. Skeletal muscle mass was measured by bioelectrical impedance analysis and expressed as a skeletal muscle mass index (SMI). Upper and lower limb muscle strength were evaluated by hand grip strength (HGS) and isometric knee extensor muscle strength, respectively. Peak expiratory flow (PEF), maximal inspiratory pressure (MIP), and maximal expiratory pressure (MEP) were evaluated using a spirometer to demonstrate respiratory muscle strength. The relationships between respiratory muscle strength and sarcopenic indices were investigated using Pearson correlation coefficients and multiple linear regression analysis adjusted by age, height, and body mass index.ResultsMIP showed positive correlations with SMI (r=0.457 in men, r=0.646 in women; both p<0.01). MIP also correlated with knee extensor strength (p<0.01 in both sexes) and HGS (p<0.05 in men, p<0.01 in women). However, PEF and MEP had no significant correlations with these sarcopenic variables. In multivariate regression analysis, MIP was the only independent factor related to SMI (p<0.01).ConclusionAmong the respiratory muscle strength variables, MIP was the only value associated with skeletal muscle mass.

Relation Between Respiratory Muscle Strength and Skeletal Muscle Mass and Hand Grip Strength in the Healthy Elderly

“…The results of this study are also in conjunction with our previous study about the relationship between respiratory muscle strength and conventional sarcopenic indices in the young Korean population [ 28 ], in that respiratory muscle strength, markedly MIP, and various sarcopenic indices are inter-related, which is due to sarcopenia. In our previous study, MIP was the only value associated with SMM and limb muscle function.…”

Muscle Mass Loss Is a Potential Predictor of 90‐Day Mortality in Older Adults with Aspiration Pneumonia

“…Individuals with AP with low muscle mass may be unable to expectorate aspirates or secretions sufficiently as a result of lack of respiratory muscle strength. Inspiratory pressure is also known to be correlated with low muscle mass . Furthermore, systemic inflammation caused by AP may elevate muscle protein catabolism, which depletes muscle mass and leads to further muscle decline and weakness; this extensive loss of protein may ultimately lead to death.…”

“…Inspiratory pressure is also known to be correlated with low muscle mass. 21 Furthermore, systemic inflammation caused by AP may elevate muscle protein catabolism, which depletes muscle mass and leads to further muscle decline and weakness; 22 this extensive loss of protein may ultimately lead to death. The inability of low ASMI to predict 30-day mortality may be because death within 30 days of presentation is strongly linked to other pneumonia-related causes.…”

Relationships between Spinal Sarcopenia and Spinal Sagittal Balance in Older Women

“…HGS was measured using a hand-grip dynamometer (T.K.K.5401; Takei Scientific Instruments, Tokyo, Japan), 10) as described previously. 11) Briefly, participants were asked to perform the following while sitting in a straight-backed chair with their feet flat on the floor: adduct and neutrally rotate the shoulder, flex the elbow to 90°, and place the forearm in a neutral position with the wrist between 0° and 30° extension and between 0° and 15° ulnar deviation. Participants were instructed to squeeze the handle as hard as possible for 3 seconds, and the maximum contraction force (kg) was recorded.…”