Relationship between intestinal microbiota, diet and biological systems: an integrated view

Ferreira, Rosângela dos Santos; Mendonça, Lígia Aurélio Bezerra Maranhão; Ribeiro, Camila Fontoura Acosta; Calças, Natalí Camposano; Guimarães, Rita de Cássia Avellaneda; Nascimento, Valter Aragão do; Freitas, Karine de Cássia; Carvalho, Cristiano Marcelo Espínola; Castro, Alinne Pereira de; Franco, Octávio Luiz

doi:10.1080/10408398.2020.1836605

Cited by 22 publications

(16 citation statements)

References 268 publications

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“…The antioxidant activity of phenolic compounds can be an alternative to promote the maintenance and recovery of the balance of the intestinal microbiota since these compounds can stimulate the secretion of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and peroxiredoxins that blocking on ROS or stimulating endogenous defense system [ 86 ].…”

Section: Antioxidant Activity Of Honeymentioning

confidence: 99%

Phenolic Compounds in Honey and Their Relationship with Antioxidant Activity, Botanical Origin, and Color

et al. 2021

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Honey has been employed since antiquity due to its sensory, nutritional, and therapeutic properties. These characteristics are related to its physical and chemical composition. For example, phenolic compounds are substances that can determine antioxidant activity, as well as sensory characteristics, and can be employed as biomarkers of floral and geographical origin. This has generated a growing interest in the study of phenolic compounds and their influence in the intrinsic properties of this beekeeping product. This review aims to summarize, analyze, and update the status of the research that demonstrates the role of phenolic compounds in antioxidant activity, botanical-geographical origin, and the sensory characteristics of honey. These phenolic compounds, according to various results reported, have great relevance in honey’s biological and functional activity. This leads to research that will link phenolic compounds to their floral, geographical, productive, and territorial origin, as well as some sensory and functional characteristics.

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Section: Antioxidant Activity Of Honeymentioning

confidence: 99%

Phenolic Compounds in Honey and Their Relationship with Antioxidant Activity, Botanical Origin, and Color

et al. 2021

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“…Dysbiosis also causes an increase in intestinal permeability due to exposure to molecular patterns, leading to a chronic inflammatory process that can result in diseases in all biological systems. 20 Of particular interest is the relationship between indigenous microbiota, dysbiosis, and the kidney.…”

Section: Microbiota and Biological Systemsmentioning

confidence: 99%

The Microbiota and Kidney Transplantation: Influence on the Graft

Salvadori

Tsalouchos

2021

EMJ Urol

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The gut microbial community may be associated with complications after kidney transplantation. The indigenous microbiota has a significant and protective function that influences the transplant recipient response. Genetic or environmental factors may modify the indigenous microbiota and pathobionts appear. In this condition, several disturbances of the kidney graft may be observed. These include acute rejection, infection, diarrhoea, disturbance in the induction of tolerance, and modification of immunosuppressive drug metabolism. Recently, the use of prebiotics, probiotics, and synbiotics has been demonstrated to be effective in normalising these conditions and in restoring the generation of the normal indigenous microbiota. An improved understanding of the function and composition of the indigenous microbiota may help in finding further solutions to stabilise the microbiota after kidney transplantation.

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“…well documented. However, various mechanisms have been hypothesized to explain the beneficial effects rendered by probiotics (46)(47)(48)(49) including improvement of digestion, inhibition of pathogenic bacteria in the gastrointestinal tract, reduction of blood pressure and high blood glucose levels, improvement of intestinal health, reduction in serum cholesterol levels, toxin degradation, production of cofactors and vitamins, upregulation of the immune system, antiinflammatory potential, and prevention of tumors and cancers (6-8, 11, 31, 46, 50-54). Probiotics-mediated molecular strategies involved in promoting health-associated phenotype and alleviating disease-associated phenotype are summarized in Tables 1, 2, respectively.…”

Section: Introductionmentioning

confidence: 99%

Probiotics, their action modality and the use of multi-omics in metamorphosis of commensal microbiota into target-based probiotics

et al. 2022

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This review article addresses the strategic formulation of human probiotics and allows the reader to walk along the journey that metamorphoses commensal microbiota into target-based probiotics. It recapitulates what are probiotics, their history, and the main mechanisms through which probiotics exert beneficial effects on the host. It articulates how a given probiotic preparation could not be all-encompassing and how each probiotic strain has its unique repertoire of functional genes. It answers what criteria should be met to formulate probiotics intended for human use, and why certain probiotics meet ill-fate in pre-clinical and clinical trials? It communicates the reasons that taint the reputation of probiotics and cause discord between the industry, medical and scientific communities. It revisits the notion of host-adapted strains carrying niche-specific genetic modifications. Lastly, this paper emphasizes the strategic development of target-based probiotics using host-adapted microbial isolates with known molecular effectors that would serve as better candidates for bioprophylactic and biotherapeutic interventions in disease-susceptible individuals.

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Relationship between intestinal microbiota, diet and biological systems: an integrated view

Cited by 22 publications

References 268 publications

Phenolic Compounds in Honey and Their Relationship with Antioxidant Activity, Botanical Origin, and Color

Phenolic Compounds in Honey and Their Relationship with Antioxidant Activity, Botanical Origin, and Color

The Microbiota and Kidney Transplantation: Influence on the Graft

Probiotics, their action modality and the use of multi-omics in metamorphosis of commensal microbiota into target-based probiotics

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