2015
DOI: 10.1155/2015/127596
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Background. Although the link between hyperuricemia and metabolic syndrome had been recognized, the association of the dyslipidemia among individuals with hyperuricemia remains not comprehensively assessed. Methods. Using NHANES III study, we examined the relation between serum lipid profiles and different serum uric acid levels, including serum total cholesterol, LDL cholesterol, triglycerides, HDL cholesterol, apolipoprotein-B, lipoprotein (a), apolipoprotein AI, ratio of triglycerides to HDL cholesterol, an… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

28
107
1
2

Year Published

2016
2016
2022
2022

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 166 publications
(138 citation statements)
references
References 31 publications
28
107
1
2
Order By: Relevance
“…31 Our study results are consistent with that there was a significant rise in blood sugar levels as depicted in Tables 2 and 3. There are reported studies suggesting increased uric acid levels are associated with alteration in lipid levels and positively correlated to hypertriglyceridemia, hypercholesterolemia and increased arterial tone, whereas HDL levels were inversely correlated with serum uric acid levels. 32,33 In our study there was slight elevation triglycerides and total cholesterol but values were not statistically significant as compared to control group. In addition there is correlation between serum uric acid levels and elevated hs-CRP, which in turn associated with stroke, cardiovascular events and immunological diseases like psoriasis.…”
contrasting
confidence: 58%
“…31 Our study results are consistent with that there was a significant rise in blood sugar levels as depicted in Tables 2 and 3. There are reported studies suggesting increased uric acid levels are associated with alteration in lipid levels and positively correlated to hypertriglyceridemia, hypercholesterolemia and increased arterial tone, whereas HDL levels were inversely correlated with serum uric acid levels. 32,33 In our study there was slight elevation triglycerides and total cholesterol but values were not statistically significant as compared to control group. In addition there is correlation between serum uric acid levels and elevated hs-CRP, which in turn associated with stroke, cardiovascular events and immunological diseases like psoriasis.…”
contrasting
confidence: 58%
“…Studies (Peng et al 2015;Xu et al 2014) have shown that serum lipid profiles are closely associated with serum uric acid levels. Lysophosphatidylcholine (LPC) regulates a variety of cellular functions and it plays a major role in a number of diseases.…”
Section: Discussionmentioning
confidence: 99%
“…Studies, however, have demonstrated that an excessive amount of uric acid is correlated with the risk of cardiovascular disease (Hongo et al, 2010; Trepiccione and Perna, 2015). Hyperuricemia has been associated with abdominal obesity (Godin et al, 2015), inflammation (Baldwin et al, 2011), type 2 diabetes (Dehghan et al, 2008), dyslipidemia (Peng et al, 2015), and metabolic syndrome (Sagodi et al, 2015). An excessive amount of uric acid is considered to be a mediator of proinflammatory endocrine imbalance in adipose tissue, contributing to the development of dyslipidemia and low-grade inflammation (Baldwin et al, 2011).…”
Section: Introductionmentioning
confidence: 99%