Relationship Between Hemoglobin and Blood Pressure Levels in the Context of Chronic Morbidity Among Older Adults Residing in a Developing Country: A Community-Level Comparative Cross-Sectional Study

Ghosh, T. K.; Rehman, Tanveer; Ahamed, Farhad

doi:10.7759/cureus.19540

Cited by 4 publications

(2 citation statements)

References 19 publications

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“…Moving on to biochemical parameters, studies done on the complementation of herbs and anti-hypertensive drugs in relation to hemoglobin measurements are scarce worldwide. However, a study by Ghosh (2021) in India reported that individuals with hypertension that complement herbs usually have Hb readings of less than 11.5 g/dL which would fall in the lowlevel group (41). Thus, this current study sheds light on measurements of hemoglobin among participants that are actively complementing herbs with drugs which shows mostly normal levels of hemoglobin.…”

Section: Highmentioning

confidence: 67%

Thirty-minute Ambulatory Blood Pressure and Blood Biochemistry Measurements in Adults With Hypertension Using Herbs: A Cross-sectional Study

Francis,

Lim,

Mat

et al. 2023

MJMHS

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Introduction: Introduction: Globally, there is a growing interest of herbs usage among hypertensive patients. The aim of study was to investigate thirty-minute ambulatory blood pressure (ABP), blood biochemistry measurements and associated factors among hypertensive adults using herbs. Methods: This cross-sectional study was performed among hypertensive adults complementing herbs and attending primary care clinics in Kinta Valley, Perak. Data was collected using standard International Complementary and Alternative Medicine Questionnaire (I-CAMQ) and measurements of thirty-minute ABP and blood biochemistry were conducted using ambulatory blood pressure monitor and point of care units respectively. Results: A total of 86 hypertensive adults using 55 herb combinations were recruited. 80.3% commonly used traditional Chinese medicine, ulam and fenugreek for more than one year. The median age of the participants was 63. The participants complementing herbs had means’ for waist-hip ratio and BMI in the high (0.92 ± 0.07) and overweight (27.14 ± 5.63) range respectively. Mean ± SD reading of systolic blood pressure was 138 ± 14.27 mm/Hg and 81.4% had normal hemoglobin levels. The mean ± SD of total cholesterol and low-density lipoprotein were normal; 166.81 ± 39.40 mg/dl and 85.15 ± 34.34 mg/dl with higher triglyceride readings 181.02 ± 61.24 mg/dl. SBP (>140 mm/Hg) and age range 61-70, waist/hip ratio (high risk for CVDs) among females and Malay ethnicity were associated with higher TC (p=0.003), HDL (p=0.006), LDL (p=0.001) and Chol/HDL (p=0.036). Conclusion: Complementing drugs with herbs associated with patients aged above 60, females and the Malay ethnicity. The patients’ attitude of complementing drugs with herbs showed no impact on the measured physiological and biochemical parameters. A randomized controlled trial with a fixed herb regime is warranted.

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Section: Highmentioning

confidence: 67%

Thirty-minute Ambulatory Blood Pressure and Blood Biochemistry Measurements in Adults With Hypertension Using Herbs: A Cross-sectional Study

Francis,

Lim,

Mat

et al. 2023

MJMHS

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“…19 Numerous studies showed that haemoglobin level positively correlates with blood pressure. [20][21][22] Severe COVID-19 is accompanied by low haemoglobin levels along with increased serum ferritin. 23 Ferritin-haemoglobin ratio is known to be an important prognostic factor in patients with advanced non-small-cell lung cancer.…”

Section: Methodsmentioning

confidence: 99%

Ferritin-haemoglobin ratio as a predictor of severity and fatal outcome in patients with Covid-19

Skakun,

Seredyuk,

Fedorov

et al. 2023

Scripta Medica

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Background/Aim: Although ferritin and haemoglobin were well-studied for adverse outcome prediction in COVID-19 patients, a ferritin-haemoglobin ratio (FHR) was studied poorly. The study aimed to evaluate the prognostic ability of FHR at hospital admission in hypertensive and non-hypertensive patients with COVID-19. Methods: The study included 135 patients hospitalised for COVID-19-associated pneumonia. The 78.5 % of patients were hypertensive. Results: FHR at admission was higher in patients with critical condition (39.8 [17.1-83.0]) than in patients with moderate (22.0 [12.1-32.1], p = 0.01) and severe condition (34.6 [15.1-64.5], p = 0.01). FHR was higher in patients who required supplemental oxygen (40.4 [29.4-47.8]) than in patients without the need for supplemental oxygen (22.0 [18.0-25.5]) (p = 0.001). FHR at admission was higher in non-survivors (40.1 [24.6-95.9]) than in survivors (24.5 [21.6-28.4]) (p = 0.047). FHR showed weak discriminative ability for the prediction of severe/critical conditions in hypertensive patients (AUC = 0.636, p = 0.015) and all (hypertensive and non-hypertensive patients) patients (AUC = 0.658, p = 0.001), whereas FHR had an acceptable discriminative ability in non-hypertensive patients (AUC = 0.764, p = 0.015). There was an acceptable discriminative ability of FHR for in-hospital mortality prediction in hypertensive patients (AUC = 0.717, p = 0.029). Patients with FHR > 33.98 (Youden index, 0.39) had higher odds of severe/critical clinical condition (OR: 4.57; 95 % CI: 1.87-11.18; p = 0.001). FHR of > 37.64 (Youden index, 0.55) was associated with higher in-hospital mortality among hypertensive patients (OR: 12.06; 95 % CI: 2.44-59.71; p = 0.002). There was no difference in AUC for the discriminative ability of FHR regarding severe/ critical condition (p = 0.296) and mortality (p = 0.663) in hypertensive and non-hypertensive patients. Conclusion: FHR at admission of > 33.98 is a predictor of severe/critical COVID-19 in both hypertensive and non-hypertensive patients. FHR of > 37.64 is a predictor of in-hospital mortality in hypertensive patients. There was no significant difference in the discriminative ability of FHR between hypertensive and non-hypertensive patients.

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Prevalence of anemia and associated factors among adult hypertensive patients in Referral Hospitals, Amhara Regional State

Gela,

Belay,

Chilot

et al. 2023

Sci Rep

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Anemia is a risk factor for adverse cardiovascular disease outcomes in hypertensive patients. Chronic anemia increases preload, reduces afterload, and leads to increased cardiac output in hypertension patients. In the long term, this may result in maladaptive left ventricular hypertrophy, which in turn is a well-recognized risk factor for cardiovascular disease outcomes and all-cause mortality in hypertension. Low hemoglobin and hematocrit levels might be strongly indicate hypertensive end-organ damage, specifically kidney failure. Therefore, this study determined the prevalence of anemia and associated factors among hypertensive patients in Referral Hospitals, Amhara Regional State, Ethiopia, in 2020. An institution-based cross-sectional study was conducted in Amhara Regional Referral Hospitals from February 20 to April 30, 2020. Random and systemic sampling techniques were used to select 428 study participants. Data were entered and coded in to Epi data version 3.0 and then exported into STATA 14 for analysis. In bivariable logistic regression, variables with a p-value of < 0.25 were included in multivariable logistic regression. Using a 95% confidence interval, variables having a p-value ≤ 0.05 in multivariable logistic regression were declared as statistically significant variables. In this study, a total of 428 study participants were involved with 99.5% response rate. The prevalence of anemia among hypertensive patients was 17.6%, with a 95% CI (14.3–21.5%). Estimated glomerular filtration rate (eGFR) < 90 ml/min (AOR = 2.77, 95% CI 1.56- 4.92)], duration of hypertension (HTN) ≥ 5 years (AOR = 2.37, 95% CI 1.36–4.15), uncontrolled blood pressure (AOR = 1.91, 95% CI 1.08–3.35), and higher pulse pressure (AOR = 1.05 (95% CI 1.02–1.08) were significantly associated with anemia. Nearly one out of five hypertensive patients had anemia. Impaired estimated glomerular filtration rate, duration of HTN, blood pressure status, and pulse pressure were the independent predictors of anemia among hypertensive patients. Screening hemoglobin level at a regular interval is recommended for the hypertensive patients to take an appropriate intervention.

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Relationship Between Hemoglobin and Blood Pressure Levels in the Context of Chronic Morbidity Among Older Adults Residing in a Developing Country: A Community-Level Comparative Cross-Sectional Study

Cited by 4 publications

References 19 publications

Thirty-minute Ambulatory Blood Pressure and Blood Biochemistry Measurements in Adults With Hypertension Using Herbs: A Cross-sectional Study

Thirty-minute Ambulatory Blood Pressure and Blood Biochemistry Measurements in Adults With Hypertension Using Herbs: A Cross-sectional Study

Ferritin-haemoglobin ratio as a predictor of severity and fatal outcome in patients with Covid-19

Prevalence of anemia and associated factors among adult hypertensive patients in Referral Hospitals, Amhara Regional State

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