Relationship between disease and disease severity and semaphorin 5A and hemogram level in obsessive–compulsive disorder

Karataş, Kader Semra; Bahçeci, İ̇lkay; Telatar, Tahsin Gökhan; Bahçeci, Bülent; Hocaoğlu, Çiçek

doi:10.1080/08039488.2021.1896779

Cited by 3 publications

(7 citation statements)

References 40 publications

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“…Furthermore, monocyte count increased in patients with BP, DD, and schizophrenia (Mazza et al 2019). It had been reported that the MLR increased in patients diagnosed with OCD for the first time, which supports the inflammatory etiopathogenesis of this disease and may be used in determining the disease severity (Karatas et al 2021). The results of this study indicate that increased MLR levels in patients with DD may be an important marker in studies on the etiopathogenesis of psychiatric diseases.…”

Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...supporting

confidence: 74%

“…Some studies reported that there were changes in PLT serotonin levels in patients with mood disorders, and these levels may be used as a marker for increased cardiovascular mortality, especially in patients with DD (Camacho and Dimsdale 2000). The PLT count decreases and PDW increases in patients with OCD (Karatas et al 2021). Increased MPV in patients with BD has been associated with inflammation (Mert and Terzi 2016).…”

Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...mentioning

confidence: 99%

“…Recent studies have investigated the PLR (Mazza et al 2019;Balta et al 2013), which is affected least by external factors, and have evaluated it together with NLR as another inflammatory and prognostic marker (39). NLR and PLR levels are associated with the severity of disease in patients with schizophrenia, BD, DD, and OCD (Mazza et al 2019;Karatas et al 2021;Kulaksizoglu and Kulaksizoglu 2016). The NLR and PLR were high in patients with schizophrenia (Moody and Miller 2018; Kulaksizoglu and Kulaksizoglu 2016).…”

Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...mentioning

confidence: 99%

“…The NLR and PLR were high in patients with schizophrenia (Moody and Miller 2018; Kulaksizoglu and Kulaksizoglu 2016). In addition, recent studies show that monocyte counts and MLR obtained using a hemogram are prominent markers of inflammation in psychiatric diseases (Karatas et al 2021). Monocyte activation may be a marker of inflammation in patients with DD (Sunbul et al 2016).…”

Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...mentioning

confidence: 99%

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Investigation of the relationship between hemogram parameters and procalcitonin levels in patients with psychiatric diseases

Karataş¹,

Kilicgedigi²,

Telatar³

et al. 2021

nin

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Introduction: This study aimed to evaluate the relationship between the hemogram parameters and the levels of procalcitonin, serum C-reactive protein, and inflammation in inpatients with psychiatric disorders. Material and methods:The study population consisted of 549 inpatients treated between January 2018 and December 2020. Data were obtained retrospectively from computer records and inpatient files. Only the first hospitalization of each patient was evaluated, and 199 patients were included in the study. The researchers examined the parameters including platelet activation, neutrophil lymphocyte ratio, monocyte lymphocyte ratio, platelet count, mean platelet volume, platelet distribution width, platelet lymphocyte ratio, and procalcitonin levels in patients and compared them with findings obtained from a control group. Results: Increased levels of C-reactive protein and decreased levels of platelets were observed in patients with schizophrenia, bipolar disorder, depressive disorder, and anxiety disorder. Increased platelet distribution width, platelet lymphocyte ratio, and neutrophil lymphocyte ratio were observed in patients with schizophrenia. The patients with bipolar disorder had increased mean platelet volume while patients with depressive disorder had an increased monocyte lymphocyte ratio. Procalcitonin levels increased in patients with anxiety disorder and depressive disorder. Discussion: Platelet activity can be an important criterion to investigate the etiopathogenesis underlying the inflammatory process in schizophrenia, bipolar disorder, depressive disorder, and anxiety disorders. To our knowledge, this is the first study to describe a positive correlation between increased monocyte lymphocyte ratio and procalcitonin levels in depressive disorder, and a positive correlation between increased procalcitonin levels and anxiety disorder and depressive disorder.

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Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...supporting

confidence: 74%

Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...mentioning

confidence: 99%

Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...mentioning

confidence: 99%

Section: Crp -C-reactive Protein; Wbc -White Blood Cells; Hct -Hemato...mentioning

confidence: 99%

See 2 more Smart Citations

Investigation of the relationship between hemogram parameters and procalcitonin levels in patients with psychiatric diseases

Karataş¹,

Kilicgedigi²,

Telatar³

et al. 2021

nin

Self Cite

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“…SEMA5A upregulation has been related to enhanced T‐cell activation in rheumatoid arthritis 4 and several psychiatric and neurodegenerative diseases. 5 Alterations of TAF15 , which encodes a member of the TET family of RNA‐binding proteins, have been described in amyotrophic lateral sclerosis and frontotemporal dementia. 6 , 7 In oncology, high SEMA5A expression was related to poor prognosis in multiple myeloma patients 8 and TAF15 ‐ ZNF384 gene fusion have been described in a rare form of acute lymphoblastic leukemia.…”

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confidence: 99%

Correspondence comprehensive characterization of a brainstem aggregoma (light and heavy chain deposition disease)

et al. 2023

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Neurophysiological cognitive assessment and its association with neutrophil to lymphocyte ratio

Rajprabha,

Sharma,

Sorout

et al. 2023

Vestn. Ross. univ. družby nar., Ser. Med.

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Relevance. Cognition is an important physiological and higher mental functions in human being. There are various studies showing that inflammatory condition could negatively affect fronto temporal cognitive abilities such as memory, attention and executive functions. A non-invasive test P300 a component of Auditory events related potentials and Mini mental state examination (MMSE), a questionnaire based test reflect cognitive function, and haematological parameter neutrophil/lymphocyte ratio (NLR) is a convenient parameter of systemic inflammation. Aim of present study was to assess the cognitive function assessment by P-300, MMSE and academic performance and find an association with neutrophil to lymphocyte ratio in first year medical students. Materials and Methods. This was an observational study conducted on 79 first year medical students of age group 18-25 years in the department of physiology RUHS College of medical sciences Jaipur. For cognitive assessment non-invasive test P300, MMSE and academic performance was recorded. A haematological parameter NLR was calculated by dividing the absolute neutrophil count with the absolute lymphocyte count. To find an association statistical analysis was done by MEDCALC 16.4 version software. Results and Discussion. The association between P-300 amplitude and latency and MMSE with NLR was found non-significant. Marks have a significant positive correlation with NLR (0.015). Conclusion. In the present study neurocognitive function test P-300 and MMSE found non-significant association with inflammatory marker NLR although academic performance (marks) have a significant positive correlation with NLR.

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Relationship between disease and disease severity and semaphorin 5A and hemogram level in obsessive–compulsive disorder

Cited by 3 publications

References 40 publications

Investigation of the relationship between hemogram parameters and procalcitonin levels in patients with psychiatric diseases

Investigation of the relationship between hemogram parameters and procalcitonin levels in patients with psychiatric diseases

Correspondence comprehensive characterization of a brainstem aggregoma (light and heavy chain deposition disease)

Neurophysiological cognitive assessment and its association with neutrophil to lymphocyte ratio

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