Relation of Brain Natriuretic Peptide to Myocardial Performance Index in Adults With Congenital Heart Disease

The BNP concentrations and exercise capacity assessment with cardiopulmonary stress test in cyanotic adult patients with congenital heart diseases

“…B-type natriuretic peptide is well validated marker of heart failure [17,23]. BNP levels were documented to increase in patients with pressure as well as volume overload of the right [12][13][14][24][25][26]28,29] and left ventricle [5,27], as well as in patients with single ventricle morphology [5,37,38]. Our study provides an evidence that BNP levels increase along with the worsening NYHA functional class, consistently with findings from Bolger et al [6].…”

ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary

“…Tissue Doppler evaluation of myocardial acceleration during isovolumic contraction has been validated as a sensitive, noninvasive method to assess RV contractility (161,162). The myocardial performance index has the advantage of representing indices of both systolic and diastolic function without geometric constraints and has shown a relationship to brain natriuretic peptide levels in ACHD patients (163). The coronary anatomy may be difficult to evaluate by echocardiography in the adult patient.…”

ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary

“…161,162 The myocardial performance index has the advantage of representing indices of both systolic and diastolic function without geometric constraints and has shown a relationship to brain natriuretic peptide levels in ACHD patients. 163 The coronary anatomy may be difficult to evaluate by echocardiography in the adult patient.…”