Reinforcement of bio-apatite by zinc substitution in the incisor tooth of a prawn

Bentov, Shmuel; Palmer, Benjamin A.; Bar‐On, Benny; Shelef, Yaniv; Aflalo, Eliahu D.; Sagi, Amir

doi:10.1016/j.actbio.2020.07.039

Cited by 15 publications

(14 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unlike Fdoping, the incorporation of Zn as a cationic trace element in HA/FA crystals is less observed in fish teeth. However, Zn incorporation in the incisors of a freshwater prawn (Macrobrachium rosenbergii) was shown to enhance its hardness in a recent report [78]. Similar correlation between the local Zn concentration and properties was also reported in the toothed jaws of a marine worm, Nereis limbata [79].…”

Section: Design Strategies At the Materials Levelsupporting

confidence: 60%

Black Drum Fish Teeth: Built for Crushing Mollusk Shells

et al. 2021

View full text Add to dashboard Cite

Section: Design Strategies At the Materials Levelsupporting

confidence: 60%

Black Drum Fish Teeth: Built for Crushing Mollusk Shells

et al. 2021

View full text Add to dashboard Cite

“…reported that Mg-rich calcite nanoparticles segregate during or after transformation from amorphous to crystalline phase in the brittlestar lenses, where the coherent nanoprecipitates can induce compressive stresses on the host matrix and strengthen the biomineral [ 52 ]. In addition, Zn-substituted apatite was found in the incisor teeth of a prawn and a clear correlation between zinc substitution level and stiffness and hardness was observed [ 55 ]. Here, calcite mesocrystals also form via attachment of amorphous nanoparticles and Zn-rich regions segregate during crystallization.…”

Section: Discussionmentioning

confidence: 99%

Bioprocess inspired formation of calcite mesocrystals by cation-mediated particle attachment mechanism

Wang

Yuan

Huang

et al. 2023

National Science Review

View full text Add to dashboard Cite

Calcite mesocrystals were proposed and have been widely reported to form in the presence of polymer additives via oriented assembly of nanoparticles. However, the formation mechanism and the role of polymer additives remain elusive. Here, inspired by the biomineralization process of sea urchin spine comprising magnesium calcite mesocrystals, we show that calcite mesocrystals could also be obtained via attachment of amorphous calcium carbonate (ACC) nanoparticles in the presence of inorganic zinc ions. Moreover, we demonstrate that zinc ions can induce the formation of temporarily stabilized amorphous nanoparticles of less than 20 nm at a significantly lower calcium carbonate concentration as compared to pure solution, which is energetically beneficial for the attachment and occlusion during calcite growth. The cation-mediated particle attachment crystallization significantly improves our understanding of mesocrystal formation mechanisms in biomineralization and offers new opportunities to bioprocess inspired inorganic ions regulated materials fabrication.

show abstract

“…When [CO 3 2– ] ≥ 6.5 wt %, such that nearly every cell contains one CO 3 2– ion, the crystallinity of minerals is significantly altered . Fluoride can promote crystal maturation and make teeth more resistant to acid attack. , An increase in F, Zn, or Fe results in an accompanying increase in the stiffness and hardness of enamel. − Magnesium is distributed in an intergranular phase at the grain boundaries of human and rodent enamel and regulates HA crystallization by stabilizing its precursor, amorphous calcium phosphate. , Substitution of Mg 2+ for Ca 2+ produces a contraction of the a -axis in synthetic HA and reduces the crystal size. , Magnesium is an inhibitor of mineral growth in solutions containing Ca 2+ , phosphate, and apatite crystal seeds . Similarly, our SEM and EDS analyses show that the Mg concentration in pseudoosteodentine of T.…”

Section: Discussionmentioning

confidence: 99%

“… 38 , 39 An increase in F, Zn, or Fe results in an accompanying increase in the stiffness and hardness of enamel. 39 − 41 Magnesium is distributed in an intergranular phase at the grain boundaries of human and rodent enamel and regulates HA crystallization by stabilizing its precursor, amorphous calcium phosphate. 39 , 42 Substitution of Mg 2+ for Ca 2+ produces a contraction of the a -axis in synthetic HA and reduces the crystal size.…”

Section: Discussionmentioning

confidence: 99%

Gradient Magnesium Content Affects Nanomechanics via Decreasing the Size and Crystallinity of Nanoparticles of Pseudoosteodentine of the Pacific Cutlassfish, Trichiurus lepturus Teeth

Tang

et al. 2022

ACS Omega

View full text Add to dashboard Cite

The formation of biomaterials such as enamel, dentin, and bone is important for many organisms, and the mechanical properties of biomaterials are affected by a wide range of structural and chemical factors. Special dentins exist in extant aquatic gnathostomes, and many more are present in fossils. When a layer of compact orthodentine surrounds the porous osteodentine core in the crown, the composite dentin is called pseudoosteodentine. Using various high-resolution analytical techniques, including micro-computed tomography (micro-CT), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), Raman spectroscopy, and nanoindentation, we analyzed the micro-and nanostructures, chemical composition, and mechanical properties of pseudoosteodentine in the Pacific cutlassfish, Trichiurus lepturus teeth. Nanoscale oval-shaped hydroxyapatite (HA) crystals were distributed in a disordered manner in the pseudoosteodentine, and a cross-sectional analysis showed that the mineral crystallinity and crystalline particle size of the outer orthodentine were greater than those of middle and inner osteodentine. Moreover, the outer orthodentine comprised a mixture of smaller crystals and larger, more mature crystals. The nano-hardness and nano-stiffness of outer orthodentine were significantly higher than those of middle and inner osteodentine along a radical direction. The hardness and stiffness of pseudoosteodentine were inversely proportional to its magnesium (Mg) content. These data are consistent with the concept that Mg delays crystal maturation. The crystal size, crystallinity, nano-hardness, and nano-stiffness of pseudoosteodentine all decreased commensurately with the increase of its Mg concentration. The pseudoosteodentine of T. lepturus also can be regarded as a functional gradient material (FGM) because its mechanical properties are closely related to its chemical composition and nanostructure. Special pseudoosteodentine may therefore serve as a design standard for biomimetic synthetic mineral composites.

show abstract

Reinforcement of bio-apatite by zinc substitution in the incisor tooth of a prawn

Cited by 15 publications

References 37 publications

Black Drum Fish Teeth: Built for Crushing Mollusk Shells

Black Drum Fish Teeth: Built for Crushing Mollusk Shells

Bioprocess inspired formation of calcite mesocrystals by cation-mediated particle attachment mechanism

Gradient Magnesium Content Affects Nanomechanics via Decreasing the Size and Crystallinity of Nanoparticles of Pseudoosteodentine of the Pacific Cutlassfish, Trichiurus lepturus Teeth

Contact Info

Product

Resources

About