volume 66, issue 9, P5298-5304 1992
DOI: 10.1128/jvi.66.9.5298-5304.1992
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L P Perera, J D Mosca, W T Ruyechan, J Hay

Abstract: Varicella-zoster virus (VZV), a neurotropic alphaherpesvirus, is the etiologic agent of chicken pox and shingles (zoster) in humans. Using an in vitro transient expression assay, we have evaluated the ability of the putative immediate early VZV genes, ORF4, ORF61, and 0RF62 (the analogs of the herpes simplex virus ai27, aO, and ca4 genes, respectively), to modulate the expression of VZV genes of different putative kinetic classes in a human T lymphocyte cell line. These cells are of the type in which VZV can b…

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