Biochemical Pharmacology volume 78, issue 9, P1198-1204 2009 DOI: 10.1016/j.bcp.2009.06.006 View full text
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N. Matheus, C. Mendoza, R. Iceta, J.E. Mesonero, A.I. Alcalde

Abstract: ABSTRACTSerotonin plays a critical role in the regulation of intestinal physiology. The serotonin transporter (SERT) expressed in the intestinal epithelium determines 5-HT availability and activity. The serotoninergic system and SERT activity have been described as being altered in chronic intestinal pathologies such as inflammatory diseases. Adenosine has also been shown to be involved in a variety of intestinal functions and to play a central role in the regulation of inflammatory responses of injured tissu…

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