Regular use of ibuprofen reduces rat penile prostaglandins and induces cavernosal fibrosis

El-Kamshoushi, A.; Hassaan, Passainte S.; Nabil, Iman; Ossama, Heba; Omar, Salma Samir

doi:10.1080/01480545.2020.1822859

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2023

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“…As noticed from the obtained results, ibuprofen and ASA cause a significant increase in serum ALP concentrations when it is used for a long duration and in high chronic doses. These results are in line with previous studies (Elkamshoushi et al, 2020).…”

Section: Discussionsupporting

confidence: 94%

Biochemical studies on the effect of prostaglandin inhibitors and willow bark extract on liver cirrhosis induced by acetylsalicylate in rats

Beltag

Ali

Sakr

et al. 2022

Journal of Medical and Life Science

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Prostaglandins (PGs) are arachidonic acid metabolites produced by the action of the enzyme cyclooxygenase (COX). Although PGs are important mediators of inflammation in various diseases, The deciduous herb, Salix mucronata Thunb (commonly called cape silver willow or safsaf willow), is widely distributed along the Nile River in Egypt. Like other willow trees, extracts from safsaf have also been used in traditional medicine. The antiinflammatory effects of Salix mucronata are the inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2

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Section: Discussionsupporting

confidence: 94%