1978
DOI: 10.1111/j.1526-4610.1978.hed1803122.x
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Abstract: SYNOPSIS Measurements of noninvasive regional cerebral blood flow (rCBF) were made by the 133Xe inhalation method in 71 patients with different types of headache and 32 age matched normal controls. Flow gray (Fg) was calculated by two compartmental analysis from the x‐ray subtracted gamma curves, and extracerebral flow indices (EFI) were calculated as an estimate of the percentage contribution by extracerebral tissues.During the headache phase, mean Fg in a group (N = 13) with classic and common migraine was s… Show more

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Cited by 203 publications
(153 citation statements)
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“…1>s However, hyperperfusion has been reported within 48 hours of the migraine attack 6 and, subsequently, also within 10 hours of the onset of the attack. 78 These observations seem to agree with our data, although the study interval is longer in these CBF studies.…”
Section: Figure 1 Bar Graph Showing Middle Cerebral Artery Diastolicmentioning
confidence: 99%
“…1>s However, hyperperfusion has been reported within 48 hours of the migraine attack 6 and, subsequently, also within 10 hours of the onset of the attack. 78 These observations seem to agree with our data, although the study interval is longer in these CBF studies.…”
Section: Figure 1 Bar Graph Showing Middle Cerebral Artery Diastolicmentioning
confidence: 99%
“…The reason this temporary sympathetic blockade may have triggered migraine headaches 24 hours later can only be postulated from data obtained from previous studies. [5][6][7][8] Abnormalities in autonomic nervous system control have been well documented in migraine, even during the headache-free interval. This autonomic imbalance in migraine consists of markedly enhanced sympathetic sensitivity with nonsignificantly reduced parasympathetic activity during headache-free periods.…”
Section: Commentsmentioning
confidence: 99%
“…6 In fact, it has been shown that extracranial blood flow is increased by 50% during migraine headache compared with that of normal subjects. 7 Thus, an increase in blood flow at the site of the migraine may result from alterations in sympathetic tone. The stimulation of trigeminal vascular reflexes secondary to pain or the release of vasoactive substances from trigeminal nerve terminals 8 are additional mechanisms that have been postulated.…”
Section: Commentsmentioning
confidence: 99%
“…Sakai and Meyer [11] found that extracranial blood flow increased by about 20% on the side affected by headache. Blau and Dexter [1,3] assessed the contribution of extracranial arteries to migraine headache by inflating a sphygmo- manometer cuff around the patient's head.…”
Section: Discussionmentioning
confidence: 99%